Technology Process of (1Z,3E)-2-butyl-1-iodo-3-propyl-1,3-heptadienyl(diphenyl)phosphine oxide
There total 1 articles about (1Z,3E)-2-butyl-1-iodo-3-propyl-1,3-heptadienyl(diphenyl)phosphine oxide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
diphenyl(2-butylethynyl)phosphine;
With
zirconocene dichloride; ethylmagnesium bromide;
In
tetrahydrofuran;
at -78 - 0 ℃;
for 3h;
4-Octyne;
In
tetrahydrofuran;
at 50 ℃;
for 3h;
With
iodine;
In
tetrahydrofuran;
at 20 ℃;
for 1h;
DOI:10.1021/jo051178c
- Guidance literature:
-
(1Z,3E)-2-butyl-1-iodo-3-propyl-1,3-heptadienyl(diphenyl)phosphine oxide;
With
n-butyllithium;
In
diethyl ether;
at -78 ℃;
for 0.5h;
4-bromo-benzaldehyde;
In
diethyl ether;
at -78 ℃;
for 1h;
With
potassium tert-butylate;
In
diethyl ether;
at -78 - 20 ℃;
DOI:10.1021/jo051178c
