L-Aspartic acid, 3-methoxy-, (3S)- (9CI)

Base Information

• Chemical Name: L-Aspartic acid, 3-methoxy-, (3S)- (9CI)
• CAS No.: 316172-74-4
• Molecular Formula: C₅H₉NO₅
• Molecular Weight: 163.13
• Mol file: 316172-74-4.mol

Synonyms:L-Aspartic acid, 3-methoxy-, (3S)- (9CI)

Chemical Property of L-Aspartic acid, 3-methoxy-, (3S)- (9CI)

Chemical Property:

• PSA: 109.85000
• LogP: -0.80180

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of L-Aspartic acid, 3-methoxy-, (3S)- (9CI)

There total 7 articles about L-Aspartic acid, 3-methoxy-, (3S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R)-β-methoxytyrosine (700816-76-8) → L-threo-β-methoxyaspartate (316172-74-4)

Guidance literature:

With oxygen; ozone; In methanol; at -78 ℃; for 1h;

DOI:10.1021/ol0513600

Reference yield:

C20H19NO7 → L-threo-β-methoxyaspartate (316172-74-4)

Guidance literature:

With diethylamine; In dichloromethane; at 20 ℃;

DOI:10.1021/acs.orglett.9b01972

Reference yield:

neamphamide A → L-threo-β-methoxyaspartate (316172-74-4)

Guidance literature:

neamphamide A; With ruthenium trichloride; sodium periodate; sodium phosphate buffer; In tetrachloromethane; water; acetonitrile; at 20 ℃; for 16h; pH=7.6;

With hydrogenchloride; In water; at 110 ℃; for 6h;

DOI:10.1021/jo0508853

upstream raw materials:

(2S,3R)-β-methoxytyrosine

Refernces

• 1、 Zampella, Angela,D'Orsi, Rosa,Sepe, Valentine,Casapullo, Agostino,Monti, Maria Chiara,D'Auria, Maria Valeria. "Concise synthesis of all stereoisomers of β-methoxytyrosine and determination of the absolute configuration of the residue in callipeltin A". . p. 3585 - 3588. Retrieved 2007/10/03.
• 2、 Shimamoto, Keiko,Shigeri, Yasushi,Yasuda-Kamatani, Yoshimi,Lebrun, Bruno,Yumoto, Noboru,Nakajima, Terumi. "Syntheses of optically pure β-hydroxyaspartate derivatives as glutamate transporter blockers". . p. 2407 - 2410. Retrieved 2007/10/03.