tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate

Base Information

• Chemical Name: tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate
• CAS No.: 870300-80-4
• Molecular Formula: C₂₀H₂₅NO₅S
• Molecular Weight: 391.488
• Mol file: 870300-80-4.mol

Synonyms:tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate

Chemical Property of tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate

There total 1 articles about tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-phenyl-propionaldehyde (104-53-0) + tert-Butyl N-hydroxycarbamate (36016-38-3) + sodium benzenesulfonate (873-55-2) → tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate (870300-80-4)

Guidance literature:

With formic acid; In methanol; water; at 20 ℃; for 20h;

DOI:10.1021/ol051766c

Reference yield: 80.0%

tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate (870300-80-4) + phenylacetylene (536-74-3) → tert-butyl 1-phenethyl-3-phenylprop-2-ynyl-N-hydroxycarbamate

Guidance literature:

phenylacetylene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.166667h;

tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate; In tetrahydrofuran; at -78 - 0 ℃; for 2.5h;

DOI:10.1021/ol051766c

Reference yield: 80.0%

tert-butyl 3-phenyl-1-(phenylsulfonyl)propyl-N-hydroxycarbamate (870300-80-4) + trans-γ-3-benzoylprop-2-en-1-ol (156386-82-2) → C24H29NO5

Guidance literature:

With potassium fluoride; C₄₆H₃₄I₄O₆; In o-xylene; at 25 ℃; for 24h; stereoselective reaction; Inert atmosphere;

DOI:10.1021/jacs.6b10660

upstream raw materials:

3-phenyl-propionaldehyde

tert-Butyl N-hydroxycarbamate

sodium benzenesulfonate