2-Methylfuran-3-carbohydrazide

Base Information

• Chemical Name: 2-Methylfuran-3-carbohydrazide
• CAS No.: 315672-60-7
• Molecular Formula: C6H8 N2 O2
• Molecular Weight: 140.142
• Hs Code.: 2932190090
• European Community (EC) Number: 673-145-6
• DSSTox Substance ID: DTXSID60365763
• Wikidata: Q82150704
• Mol file: 315672-60-7.mol

Synonyms:2-methylfuran-3-carbohydrazide;2-methyl-3-furohydrazide;315672-60-7;2-Methyl-furan-3-carboxylic acid hydrazide;2-methyl-3-furoic hydrazide;DTXSID60365763;JS-124C;HMS1784H21;BBL008410;MFCD01330023;STK073647;AKOS000116149;SB61145;2-Methylfuran-3-carboxylic acid hydrazide;CS-0307630;FT-0743891;EN300-03758;J-510052;Z56827318;2-methyl-furan-3-carboxylic acid hydrazide, AldrichCPR

Chemical Property of 2-Methylfuran-3-carbohydrazide

Chemical Property:

• Melting Point: 149.5-150 °C
• Refractive Index: 1.531
• PKA: 12.32±0.10(Predicted)
• PSA: 68.26000
• Density: 1.207g/cm³
• LogP: 1.28270
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 140.058577502
• Heavy Atom Count: 10
• Complexity: 138

Purity/Quality:

98%min ^*data from raw suppliers

2-Methyl-3-Furohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CO1)C(=O)NN

Technology Process of 2-Methylfuran-3-carbohydrazide

There total 3 articles about 2-Methylfuran-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methyl 2-methyl-3-furancarboxylate (6141-58-8) → 2-methyl-furan-3-carboxylic acid hydrazide (315672-60-7)

Guidance literature:

With hydrazine hydrate; In methanol; at 75 ℃; Inert atmosphere;

DOI:10.1021/acs.jmedchem.5b00203

Reference yield:

C14H16N3O7P → 2-methyl-furan-3-carboxylic acid hydrazide (315672-60-7) + pyridoxal 5'-phosphate (54-47-7)

Guidance literature:

In water; at 25.04 ℃; pH=6.6; pH-value; Thermodynamic data; Kinetics; Equilibrium constant;

DOI:10.1134/S0036024419020110

Reference yield:

2-methyl-3-ethoxycarbonyl-furan (28921-35-9) → 2-methyl-furan-3-carboxylic acid hydrazide (315672-60-7)

Guidance literature:

With hydrazine hydrate;

DOI:10.1021/ja01316a045 DOI:10.1021/ja01291a013

upstream raw materials:

2-methyl-3-ethoxycarbonyl-furan

methyl 2-methyl-3-furancarboxylate

Downstream raw materials:

C₁₃H₁₂IN₃O₂S

C₁₄H₁₅N₃O₃S

C₁₄H₁₅N₃O₂S

C₁₄H₁₅N₃O₂S