1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-methyl-, (4S,5S)- (9CI)

Base Information

• Chemical Name: 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-methyl-, (4S,5S)- (9CI)
• CAS No.: 315216-23-0
• Molecular Formula: C₆H₁₀O₄
• Molecular Weight: 146.143
• Mol file: 315216-23-0.mol

Synonyms:1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-methyl-, (4S,5S)- (9CI)

Chemical Property of 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-methyl-, (4S,5S)- (9CI)

Chemical Property:

• PSA: 55.76000
• LogP: -0.69240

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-methyl-, (4S,5S)- (9CI)

There total 13 articles about 1,3-Dioxane-4-carboxaldehyde, 5-hydroxy-2-methyl-, (4S,5S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(1’R)-(-)-4,6-O-ethylidene-D-glucose (13224-97-0,13224-98-1,13224-99-2,13225-00-8,13225-01-9,13225-02-0,18465-50-4,87068-63-1) → (1'R)-(-)-2,4-O-ethylidene-D-erythrose (70377-89-8,315216-23-0)

Guidance literature:

With sodium periodate; sodium hydrogencarbonate; In dichloromethane; water;

DOI:10.1021/ol0630651

Reference yield: 92.0%

4,6-(Ethylidenedioxy)-D-glucopyranose (13403-24-2) → 2,4-O-ethylidene-aldehydo-D-erythrose (901783-93-5,315216-23-0)

Guidance literature:

With sodium periodate;

Reference yield:

O4,O6-((S)-ethylidene)-L-glucose (112246-57-8) → O2,O4-((S)-ethyliden)-L-erythrose (24871-55-4,70377-89-8,87068-62-0,315216-23-0)

Guidance literature:

With sodium periodate; water; sodium hydrogencarbonate;

DOI:10.1021/ja01156a002

upstream raw materials:

4,6-O-ethylidene-D-glucopyranose

(1’R)-(-)-4,6-O-ethylidene-D-glucose

4,6-O-ethylidene-D-glucose

O⁴,O⁶-((S)-ethylidene)-L-glucose

Downstream raw materials:

(O³,O⁵-(R)-ethane-1,1-diyl-D-erythro-2-deoxy-pent-1-enitol-1-yl)-phosphonic acid lactone (Ξ)-phenyl ester

(2R,4S,5R)-4-hydroxymethyl-2-methyl-1,3-dioxan-5-ol

(-)-(S,S-trans)-3-(hydroxymethyl)oxiranebutanoic acid methyl ester

(5S,6S)-epoxy-10-formyl-(7E,9E)-decadienoic acid methyl ester