4-{2-(o-bromophenyl)-2-hydroxyethyl}-6-trifluoromethyl-2-phenylquinoline

Base Information

Chemical Name:4-{2-(o-bromophenyl)-2-hydroxyethyl}-6-trifluoromethyl-2-phenylquinoline
CAS No.:1063600-26-9
Molecular Formula:C₂₄H₁₇BrF₃NO
Molecular Weight:472.304
Hs Code.:

Synonyms:4-{2-(o-bromophenyl)-2-hydroxyethyl}-6-trifluoromethyl-2-phenylquinoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-{2-(o-bromophenyl)-2-hydroxyethyl}-6-trifluoromethyl-2-phenylquinoline

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Technology Process of 4-{2-(o-bromophenyl)-2-hydroxyethyl}-6-trifluoromethyl-2-phenylquinoline

There total 1 articles about 4-{2-(o-bromophenyl)-2-hydroxyethyl}-6-trifluoromethyl-2-phenylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 945033-50-1
6-trifluoromethyl-4-(triisopropylsilyl)methyl-2-phenylquinoline

: 6630-33-7
ortho-bromobenzaldehyde

: 1063600-26-9
4-{2-(o-bromophenyl)-2-hydroxyethyl}-6-trifluoromethyl-2-phenylquinoline

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; water; at 20 ℃;
DOI:10.1021/jo8009243

Reference yield: 40.0%

: 1063600-26-9
4-{2-(o-bromophenyl)-2-hydroxyethyl}-6-trifluoromethyl-2-phenylquinoline

: 1063600-29-2
9-trifluoromethyl-5-phenylbenzo[i]phenanthridine

Guidance literature:: 4-{2-(o-bromophenyl)-2-hydroxyethyl}-6-trifluoromethyl-2-phenylquinoline; With 2,2'-azobis(isobutyronitrile); tris-(trimethylsilyl)silane; In benzene; for 48h; Inert atmosphere; Reflux;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1021/jo8009243