3-Pyridinemethanamine,alpha-2-propenyl-,(alphaS)-(9CI)

Base Information

• Chemical Name: 3-Pyridinemethanamine,alpha-2-propenyl-,(alphaS)-(9CI)
• CAS No.: 314280-30-3
• Molecular Formula: C9H12 N2
• Molecular Weight: 148.21
• Mol file: 314280-30-3.mol

Synonyms:3-Pyridinemethanamine,a-2-propenyl-, (aS)- (9CI)

Chemical Property of 3-Pyridinemethanamine,alpha-2-propenyl-,(alphaS)-(9CI)

Chemical Property:

• PSA: 38.91000
• LogP: 2.35780

Purity/Quality:

(S)-1-PYRIDIN-3-YL-BUT-3-ENYLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Pyridinemethanamine,alpha-2-propenyl-,(alphaS)-(9CI)

There total 20 articles about 3-Pyridinemethanamine,alpha-2-propenyl-,(alphaS)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(S)-3-(1-azido-but-3-enyl)pyridine (314280-29-0) → (S)-1-(pyridin-3-yl)but-3-en-1-amine (314280-30-3)

Guidance literature:

With tin(ll) chloride; In methanol; at 20 ℃; for 3h;

DOI:10.1021/jo010386b

Reference yield: 98.0%

3-(1-azido-but-3-enyl)-pyridine → (S)-1-(pyridin-3-yl)but-3-en-1-amine (314280-30-3)

Guidance literature:

With tin(ll) chloride; In methanol; at 0 ℃; for 3h;

Reference yield: 91.0%

3-pyridinecarboxaldehyde (500-22-1) + (1R,3R,4S)-3-allyl-3-amino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one (910545-65-2) → (S)-1-(pyridin-3-yl)but-3-en-1-amine (314280-30-3)

Guidance literature:

With camphor-10-sulfonic acid; In 1,2-dichloro-ethane; at 50 ℃; for 24h;

DOI:10.1021/ja064106r

upstream raw materials:

(S)-3-(1-azido-but-3-enyl)pyridine

3-pyridinecarboxaldehyde

(1R,3R,4S)-3-allyl-3-amino-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one

(S)-2-[(S)-1-(3-pyridyl)-3-butenylamino]-3-methyl-1-butanol

Downstream raw materials:

(S)-(1-pyridin-3-yl-but-3-enyl)-carbamic acid benzyl ester