2'-O-acetyl-N₂-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin

Base Information

• Chemical Name: 2'-O-acetyl-N₂-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin
• CAS No.: 916044-84-3
• Molecular Formula: C₃₀H₃₃N₇O₇
• Molecular Weight: 603.635
• Mol file: 916044-84-3.mol

Synonyms:2'-O-acetyl-N₂-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin

Chemical Property of 2'-O-acetyl-N₂-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2'-O-acetyl-N₂-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin

There total 1 articles about 2'-O-acetyl-N₂-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4-nitrophenyl)ethanol (100-27-6) + 5-deoxy-3-O-(4-methoxybenzyl)-L-erythro-pentos-2-ulose (916044-81-0) + acetic anhydride (108-24-7) + 2,4,5-triamino-6-hydroxypyrimidine sulfate (35011-47-3) + N,N-dimethyl-formamide dimethyl acetal (4637-24-5) → 2'-O-acetyl-N2-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin (916044-84-3) + C30H33N7O7 (916044-85-4)

Guidance literature:

5-deoxy-3-O-(4-methoxybenzyl)-L-erythro-pentos-2-ulose; 2,4,5-triamino-6-hydroxypyrimidine sulfate; With sodium hydrogencarbonate; In methanol; water; for 3h; Reflux;

N,N-dimethyl-formamide dimethyl acetal; With triphenylphosphine; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

2-(4-nitrophenyl)ethanol; acetic anhydride; Further stages;

DOI:10.1016/j.tet.2009.07.043

Reference yield: 99.0%

2'-O-acetyl-N2-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin (916044-84-3) → N2-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin (916044-86-5)

Guidance literature:

With methanol; sodium methylate; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2009.07.043

upstream raw materials:

2-(4-nitrophenyl)ethanol

5-deoxy-3-O-(4-methoxybenzyl)-L-erythro-pentos-2-ulose

acetic anhydride

2,4,5-triamino-6-hydroxypyrimidine sulfate

Downstream raw materials:

N₂-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin