4-Aza-spiro[2.4]heptane-4,5-dicarboxylic acid 4-benzyl ester

Base Information

• Chemical Name: 4-Aza-spiro[2.4]heptane-4,5-dicarboxylic acid 4-benzyl ester
• CAS No.: 124032-32-2
• Molecular Formula: C₁₅H₁₇NO₄
• Molecular Weight: 275.304
• Mol file: 124032-32-2.mol

Synonyms:4-Aza-spiro[2.4]heptane-4,5-dicarboxylic acid 4-benzyl ester

Chemical Property of 4-Aza-spiro[2.4]heptane-4,5-dicarboxylic acid 4-benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 4-Aza-spiro[2.4]heptane-4,5-dicarboxylic acid 4-benzyl ester

There total 1 articles about 4-Aza-spiro[2.4]heptane-4,5-dicarboxylic acid 4-benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

5-Hydroxymethyl-4-aza-spiro[2.4]heptane-4-carboxylic acid benzyl ester (124032-29-7) → 4-Aza-spiro[2.4]heptane-4,5-dicarboxylic acid 4-benzyl ester (124032-32-2)

Guidance literature:

With chromium(VI) oxide; hydrogen cation; In acetone; at 0 ℃; for 0.333333h;

DOI:10.1016/S0040-4039(00)95211-0

Reference yield: 58.0%

4-Aza-spiro[2.4]heptane-4,5-dicarboxylic acid 4-benzyl ester (124032-32-2) → 4-Aza-spiro[2.4]heptane-5-carboxylic acid (124032-25-3)

Guidance literature:

With trimethylsilyl iodide; In acetonitrile;

DOI:10.1016/S0040-4039(00)95211-0

upstream raw materials:

5-Hydroxymethyl-4-aza-spiro[2.4]heptane-4-carboxylic acid benzyl ester

Downstream raw materials:

4-Aza-spiro[2.4]heptane-5-carboxylic acid