Toluene-4-sulfonic acid 2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester

Base Information

• Chemical Name: Toluene-4-sulfonic acid 2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester
• CAS No.: 153895-19-3
• Molecular Formula: C₄₇H₅₆O₅S
• Molecular Weight: 733.025
• Mol file: 153895-19-3.mol

Synonyms:Toluene-4-sulfonic acid 2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester

Chemical Property of Toluene-4-sulfonic acid 2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid 2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester

There total 6 articles about Toluene-4-sulfonic acid 2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

p-toluenesulfonyl chloride (98-59-9) + 2-(2-{4-[Bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethanol (177609-53-9) → Toluene-4-sulfonic acid 2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester (153895-19-3)

Guidance literature:

With sodium hydroxide; benzyltriethylammonium bromide; In dichloromethane; for 12h; Ambient temperature;

DOI:10.1021/ja954334d

Reference yield:

Potassium; 4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenolate → Toluene-4-sulfonic acid 2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester (153895-19-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / K₂CO₃ / acetonitrile / 120 h / Heating

2: 78 percent / 30percent aq. NaOH, benzyltriethylammonium bromide / CH₂Cl₂ / 12 h / Ambient temperature

With sodium hydroxide; benzyltriethylammonium bromide; potassium carbonate; In dichloromethane; acetonitrile;

DOI:10.1021/ja954334d

Reference yield:

p-isopropylbenzoic acid methyl ester (20185-55-1) → Toluene-4-sulfonic acid 2-(2-{4-[bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethyl ester (153895-19-3)

Guidance literature:

Multi-step reaction with 5 steps

1: tetrahydrofuran

2: SOCl₂ / toluene / Heating

3: 98 percent / 2.) 8 M aq. KOH / Heating

4: K₂CO₃ / acetonitrile

5: 30percent aq. NaOH, PhCH₂Et₃NBr / CH₂Cl₂

With potassium hydroxide; sodium hydroxide; thionyl chloride; benzyltriethylammonium bromide; potassium carbonate; In tetrahydrofuran; dichloromethane; toluene; acetonitrile;

DOI:10.1039/c39930001269

upstream raw materials:

p-toluenesulfonyl chloride

2-(2-{4-[Bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethanol

p-isopropylbenzoic acid methyl ester

4-tert-butylmagnesium bromide

Downstream raw materials:

C₄₇H₅₅ClO₃

{4-[2-(2-{4-[Bis-(4-tert-butyl-phenyl)-(4-isopropyl-phenyl)-methyl]-phenoxy}-ethoxy)-ethoxy]-phenyl}-methanol

Refernces

• 1、 Ashton,Ballardini,Balzani,Belohradsky,Gandolfi,Philp,Prodi,Raymo,Reddington,Spencer,Stoddart,Venturi,Williams. "Self-assembly, spectroscopic, and electrochemical properties of [n]rotaxanes". . p. 4931 - 4951. Retrieved 2007/10/03.