Technology Process of 1,1-dimethylethyl amino>-2,3-O-(1-methylethylidene)-β-D-ribo-decofuranosid>uronate
There total 11 articles about 1,1-dimethylethyl amino>-2,3-O-(1-methylethylidene)-β-D-ribo-decofuranosid>uronate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium azide; ammonium chloride;
In
N,N-dimethyl-formamide;
at 22 ℃;
for 16h;
DOI:10.1021/jo00290a028
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 82 percent / CHCl3 / 22 h / 22 °C
2: 99 percent / H2 / 10percent Pd/C / methanol / 3102.9 Torr
3: 56 percent / m-CPBA / CH2Cl2 / 0.28 h / Heating
4: 86 percent / KF / acetonitrile / 24 h / 22 °C
5: 96 percent / dicyclohexylcarbodiimde, copper(I) chloride / acetonitrile / 16 h / 35 °C
6: 84 percent / zinc dust, acetic acid / tetrahydrofuran / 0.25 h / 45 °C
7: 81 percent / cerium(IV) ammonium nitrate, HNO3 / ethanol / 0.25 h / -42 °C
8: 80 percent / L-selectride / tetrahydrofuran / 2 h / -78 °C
9: pyridine / 1 h / 0 °C
10: 100 percent / sodium azide, ammonium chloride / dimethylformamide / 16 h / 22 °C
With
pyridine; potassium fluoride; sodium azide; ammonium cerium(IV) nitrate; ammonium chloride; hydrogen; nitric acid; L-Selectride; acetic acid; 3-chloro-benzenecarboperoxoic acid; dicyclohexyl-carbodiimide; copper(l) chloride; zinc;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; chloroform; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo00290a028
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 99 percent / H2 / 10percent Pd/C / methanol / 3102.9 Torr
2: 56 percent / m-CPBA / CH2Cl2 / 0.28 h / Heating
3: 86 percent / KF / acetonitrile / 24 h / 22 °C
4: 96 percent / dicyclohexylcarbodiimde, copper(I) chloride / acetonitrile / 16 h / 35 °C
5: 84 percent / zinc dust, acetic acid / tetrahydrofuran / 0.25 h / 45 °C
6: 81 percent / cerium(IV) ammonium nitrate, HNO3 / ethanol / 0.25 h / -42 °C
7: 80 percent / L-selectride / tetrahydrofuran / 2 h / -78 °C
8: pyridine / 1 h / 0 °C
9: 100 percent / sodium azide, ammonium chloride / dimethylformamide / 16 h / 22 °C
With
pyridine; potassium fluoride; sodium azide; ammonium cerium(IV) nitrate; ammonium chloride; hydrogen; nitric acid; L-Selectride; acetic acid; 3-chloro-benzenecarboperoxoic acid; dicyclohexyl-carbodiimide; copper(l) chloride; zinc;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jo00290a028
