N-Trityl Candesartan Cilexetil

Base Information

Chemical Name:N-Trityl Candesartan Cilexetil
CAS No.:886999-34-4
Molecular Formula:C₅₂H₄₈N₆O₆
Molecular Weight:852.99
Hs Code.:
Mol file:886999-34-4.mol

Synonyms:2-Ethoxy-3-[2'-(2-trityl-2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester

Suppliers and Price of N-Trityl Candesartan Cilexetil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-TritylCandesartanCilexetil
1g
$ 1110.00

TRC
N-TritylCandesartanCilexetil
100mg
$ 140.00

Medical Isotopes, Inc.
N-TritylCandesartanCilexetil
1 g
$ 2120.00

Total 6 raw suppliers

Chemical Property of N-Trityl Candesartan Cilexetil

Chemical Property:

Purity/Quality:

98%Min ^*data from raw suppliers

N-TritylCandesartanCilexetil ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N-Trityl Candesartan Cilexetil is a titrylated impurity and precursor to Candesartan Cilexetil (C175580).

Technology Process of N-Trityl Candesartan Cilexetil

There total 3 articles about N-Trityl Candesartan Cilexetil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 99464-83-2
1-chloroethyl cyclohexyl carbonate

: 894806-43-0
2-ethoxy-1-<<2'-biphenyl-4-yl>methyl>-1H-benzimidazole-7-carboxylic acid

: 886999-34-4
2-Ethoxy-3-[2'-(2-trityl-2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester

Guidance literature:: With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 60 ℃; for 2h;
DOI:10.1021/jm00068a011

Reference yield:

: 76-83-5
trityl chloride

: 886999-34-4
2-Ethoxy-3-[2'-(2-trityl-2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / triethylamine / CH₂Cl₂ / 1 h / Ambient temperature

2: potassium iodide, potassium carbonate / dimethylformamide / 2 h / 60 °C

With potassium carbonate; triethylamine; potassium iodide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00068a011

Reference yield:

: 139481-59-7
candesartan

: 886999-34-4
2-Ethoxy-3-[2'-(2-trityl-2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / triethylamine / CH₂Cl₂ / 1 h / Ambient temperature

2: potassium iodide, potassium carbonate / dimethylformamide / 2 h / 60 °C

With potassium carbonate; triethylamine; potassium iodide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00068a011