1H-Pyrrole-3-carboxylicacid,2,5-dimethyl-4-(1-naphthalenyl)-,ethylester(9CI)

Base Information

Chemical Name:1H-Pyrrole-3-carboxylicacid,2,5-dimethyl-4-(1-naphthalenyl)-,ethylester(9CI)
CAS No.:312280-13-0
Molecular Formula:C₁₉H₁₉NO₂
Molecular Weight:293.365
Hs Code.:
Mol file:312280-13-0.mol

Synonyms:1H-Pyrrole-3-carboxylicacid,2,5-dimethyl-4-(1-naphthalenyl)-,ethylester(9CI)

Suppliers and Price of 1H-Pyrrole-3-carboxylicacid,2,5-dimethyl-4-(1-naphthalenyl)-,ethylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1H-PYRROLE-3-CARBOXYLIC ACID, 2,5-DIMETHYL-4-(1-NAPHTHALENYL)-, ETHYL ESTER 95.00%
5MG
$ 497.87

Total 1 raw suppliers

Chemical Property of 1H-Pyrrole-3-carboxylicacid,2,5-dimethyl-4-(1-naphthalenyl)-,ethylester(9CI)

Chemical Property:

PSA：42.09000
LogP:4.62840

Purity/Quality:: 1H-PYRROLE-3-CARBOXYLIC ACID, 2,5-DIMETHYL-4-(1-NAPHTHALENYL)-, ETHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrole-3-carboxylicacid,2,5-dimethyl-4-(1-naphthalenyl)-,ethylester(9CI)

There total 3 articles about 1H-Pyrrole-3-carboxylicacid,2,5-dimethyl-4-(1-naphthalenyl)-,ethylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 196311-64-5
2,6-dimethyl-4-[1]naphthyl-pyridine-3,5-dicarboxylic acid diethyl ester

: 312280-13-0
ethyl 2,5-dimethyl-4-(naphthalen-1-yl)-1H-pyrrole-3-carboxylate

Guidance literature:: With boron trifluoride diethyl etherate; tetrabutylammonium tetrafluoroborate; water; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere; Electrolysis;
DOI:10.1039/d1gc00487e

Reference yield: 60.0%

: 1791-23-7
1-(1'-naphthyl)-2-propyn-1-ol

: 141-97-9
ethyl acetoacetate

: 312280-13-0
ethyl 2,5-dimethyl-4-(naphthalen-1-yl)-1H-pyrrole-3-carboxylate

Guidance literature:: With tert-butyl carbazate; [Ru(η3-2-C3H4Me)(CO)(1,1'-bis(diphenylphosphino)ferrocene)][SbF6]; trifluoroacetic acid; In tetrahydrofuran; at 20 - 75 ℃; Inert atmosphere;
DOI:10.1002/jhet.301

Reference yield:

: 34148-71-5
diethyl 4-(naphthalene-1-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

: 312280-13-0
ethyl 2,5-dimethyl-4-(naphthalen-1-yl)-1H-pyrrole-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: dipotassium peroxodisulfate / water; acetonitrile / 55 °C / Inert atmosphere

2: boron trifluoride diethyl etherate; tetrabutylammonium tetrafluoroborate; water / tetrahydrofuran / 12 h / 20 °C / Inert atmosphere; Electrolysis

With dipotassium peroxodisulfate; boron trifluoride diethyl etherate; tetrabutylammonium tetrafluoroborate; water; In tetrahydrofuran; water; acetonitrile;
DOI:10.1039/d1gc00487e