6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

Base Information

Chemical Name:6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine
CAS No.:741685-46-1
Molecular Formula:C₂₆H₂₁F₃N₂
Molecular Weight:418.461
Hs Code.:

Synonyms:6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

Suppliers and Price of 6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

There total 6 articles about 6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

: 1027604-10-9
1-(3-diphenylphosphanyl-1,3-diphenyl-propa-1,2-dienyl)-4-(3-trifluoromethyl-phenyl)-piperazine

: 741685-46-1
6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

: diphenyl{6-phenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4,6,12b-hexahydrobenzo[c]pyrazino[1,2-a]azepin-8-yl}phosphanoxide

Guidance literature:: 1-(3-diphenylphosphanyl-1,3-diphenyl-propa-1,2-dienyl)-4-(3-trifluoromethyl-phenyl)-piperazine; In N,N-dimethyl-formamide; at 150 ℃; for 12h;

With dihydrogen peroxide; In dichloromethane; water;
DOI:10.1021/jo049586o

Reference yield: 8.0%

: 13683-01-7
Diphenylphosphonigsaeure-trimethylsilylester

: 1-(1,3-diphenyl-2-propynylidene)-4-[3-(trifluoromethyl)phenyl]hexahydro-1-pyrazinium trifluoromethanesulfonate

: 741685-46-1
6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

: [1,3-diphenyl-1-[4-[3-(trifluoromethyl)phenyl]piperazino]-2-propynyl]diphenylphosphanoxide

: diphenyl{6-phenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4,6,12b-hexahydrobenzo[c]pyrazino[1,2-a]azepin-8-yl}phosphanoxide

Guidance literature:: Diphenylphosphonigsaeure-trimethylsilylester; 1-(1,3-diphenyl-2-propynylidene)-4-[3-(trifluoromethyl)phenyl]hexahydro-1-pyrazinium trifluoromethanesulfonate; With lithium chloride; In tetrahydrofuran; at -78 - 20 ℃; for 12h;

In toluene; at 100 ℃; for 5h;
DOI:10.1021/jo049586o

Reference yield:

: 1-(1,3-diphenyl-2-propynylidene)-4-[3-(trifluoromethyl)phenyl]hexahydro-1-pyrazinium trifluoromethanesulfonate

: 741685-46-1
6,8-diphenyl-2-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine

Guidance literature:: 1-(1,3-diphenyl-2-propynylidene)-4-[3-(trifluoromethyl)phenyl]hexahydro-1-pyrazinium trifluoromethanesulfonate; With O-trimethylsilyl bis(4-chlorophenyl)phosphonite; lithium chloride; In dichloromethane; at -78 - 20 ℃; for 12h;

In toluene; at 100 ℃; for 5h;
DOI:10.1021/jo049586o