Technology Process of C53H52N4O16
There total 12 articles about C53H52N4O16 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 5 steps
1.1: 70 percent / Et3N / CH2Cl2 / 0 °C
2.1: 93 percent / 4 Angstroem molecular sieves; AgOTf / CH2Cl2 / 4 h / -5 °C
3.1: O3 / methanol; CH2Cl2 / -78 °C
3.2: NaBH4 / methanol; CH2Cl2 / 2 h / -78 - 0 °C
4.1: Et3N / CH2Cl2 / 1 h / 0 °C
5.1: 93 percent / NaN3; 18-crown-6 / dimethylformamide / 96 h / 20 °C
With
sodium azide; 18-crown-6 ether; 4 A molecular sieve; silver trifluoromethanesulfonate; ozone; triethylamine;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0008-6215(01)00213-0
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: (+/-)-CSA / benzene / 20 °C
1.2: 99 percent / aq. acetic acid / 1 h / 20 °C
2.1: 100 percent / pyridine / 48 h / 20 °C
3.1: 96 percent / AcOH; cc H2SO4 / 0 - 20 °C
4.1: 97 percent / HBr; AcOH / CH2Cl2 / 3 h / 20 °C
5.1: 93 percent / 4 Angstroem molecular sieves; AgOTf / CH2Cl2 / 4 h / -5 °C
6.1: O3 / methanol; CH2Cl2 / -78 °C
6.2: NaBH4 / methanol; CH2Cl2 / 2 h / -78 - 0 °C
7.1: Et3N / CH2Cl2 / 1 h / 0 °C
8.1: 93 percent / NaN3; 18-crown-6 / dimethylformamide / 96 h / 20 °C
With
pyridine; sodium azide; 18-crown-6 ether; 4 A molecular sieve; sulfuric acid; 10-camphorsufonic acid; hydrogen bromide; silver trifluoromethanesulfonate; ozone; acetic acid; triethylamine;
In
methanol; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1016/S0008-6215(01)00213-0
