2-(2-bromoprop-2-en-1-yl)cyclohexanone

Base Information

• Chemical Name: 2-(2-bromoprop-2-en-1-yl)cyclohexanone
• CAS No.: 53626-84-9
• Molecular Formula: C9H13 Br O
• Molecular Weight: 217.106
• Mol file: 53626-84-9.mol

Synonyms:Cyclohexanone,2-(2-bromo-2-propenyl)- (9CI); 2-(2-Bromoallyl)cyclohexanone;2-(2-bromo-2-propenyl)cyclohexanone; NSC 151702

Chemical Property of 2-(2-bromoprop-2-en-1-yl)cyclohexanone

Chemical Property:

• Vapor Pressure: 0.00982mmHg at 25°C
• Boiling Point: 264.2°Cat760mmHg
• Flash Point: 61°C
• Density: 1.314g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-bromoprop-2-en-1-yl)cyclohexanone

There total 6 articles about 2-(2-bromoprop-2-en-1-yl)cyclohexanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + 2-bromoallyl bromide (513-31-5) → 2-(2-bromo-2-propen-1-yl)cyclohexanone (53626-84-9)

Guidance literature:

cyclohexanone; 2-bromoallyl bromide; In 1,4-dioxane; for 3h; Reflux;

With hydrogenchloride; water; In 1,4-dioxane; for 1h; Reflux;

DOI:10.1021/acs.orglett.0c02272

Reference yield: 65.0%

1-(1-Cyclohexen-1-yl)pyrrolidine (1125-99-1) + 2-bromoallyl bromide (513-31-5) → 2-(2-bromo-2-propen-1-yl)cyclohexanone (53626-84-9)

Guidance literature:

1-(1-Cyclohexen-1-yl)pyrrolidine; 2-bromoallyl bromide; With triethylamine; In 1,4-dioxane; for 6h; Heating;

With hydrogenchloride; for 3h; Heating;

DOI:10.1016/j.tetlet.2004.10.145

Reference yield:

[2-(2-Bromo-allyl)-cyclohex-(E)-ylidene]-cyclohexyl-amine → 2-(2-bromo-2-propen-1-yl)cyclohexanone (53626-84-9)

Guidance literature:

With hydrogenchloride; In diethyl ether; for 2h; Yield given; Heating;

DOI:10.1021/ja9624432

upstream raw materials:

2-[(Z)-Cyclohexylimino]-cyclohexanone

2-bromoallyl bromide

1-(1-Cyclohexen-1-yl)pyrrolidine

cyclohexanone

Downstream raw materials:

2-(2-oxopropyl)cyclohexanone

2-(2-Bromo-2-propenyl)cyclohexan-1-ol

2-(2'-bromoallyl)-methylenecyclohexane

Benzyl-[2-(2-bromo-allyl)-cyclohex-(Z)-ylidene]-amine