(2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane

Base Information

Chemical Name:(2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane
CAS No.:177959-36-3
Molecular Formula:C₁₇H₁₈O₃
Molecular Weight:270.328
Hs Code.:

Synonyms:(2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane

Suppliers and Price of (2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane

There total 15 articles about (2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 177959-34-1
(2S,3S)-4-(4'-benzyloxyphenyl)-2,3-O-isopropylidenedioxy-1-p-toluenesulfonyloxybutane

: 177959-36-3
(2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane

Guidance literature:: (2S,3S)-4-(4'-benzyloxyphenyl)-2,3-O-isopropylidenedioxy-1-p-toluenesulfonyloxybutane; With hydrogenchloride; In methanol; water; at 20 ℃; for 12h;

With potassium carbonate; In methanol; at 20 ℃; for 10h;
DOI:10.1016/S0040-4020(01)01219-4

Reference yield: 73.0%

: 422321-74-2
4-(4'-benzyloxyphenyl)-1-bromobut-2-ene

: 177959-36-3
(2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane

Guidance literature:: 4-(4'-benzyloxyphenyl)-1-bromobut-2-ene; With (3a,9R,3'''a,4'"b,9'"R)-9,9'-[1,4-phthalazinediylbis(oxy)]bis[6'-(methyloxy)-10,11-dihydrocinchonan]; osmium(VIII) oxide; potassium hexacyanoferrate(III); In water; toluene; tert-butyl alcohol; at 0 ℃; for 18h;

With potassium carbonate; In methanol; at 20 ℃; for 10h;
DOI:10.1016/S0040-4020(01)01219-4

Reference yield:

: 422321-77-5
(2S,3S)-4-(4'-benzyloxyphenyl)-2,3-O-isopropylidenedioxybutan-1-ol

: 177959-36-3
(2S,3S)-4-(4'-benzyloxyphenyl)-1,2-epoxy-3-hydroxybutane

Guidance literature:: Multi-step reaction with 2 steps

1.1: 90 percent / pyridine / CH₂Cl₂ / 12 h / 20 °C

2.1: HCl / H₂O; methanol / 12 h / 20 °C

2.2: 85 percent / K₂CO₃ / methanol / 10 h / 20 °C

With pyridine; hydrogenchloride; In methanol; dichloromethane; water;
DOI:10.1016/S0040-4020(01)01219-4