C₁₀H₄ClF₆N₃S

Base Information

• Chemical Name: C₁₀H₄ClF₆N₃S
• CAS No.: 1308251-18-4
• Molecular Formula: C₁₀H₄ClF₆N₃S
• Molecular Weight: 347.671
• Mol file: 1308251-18-4.mol

Synonyms:C₁₀H₄ClF₆N₃S

Chemical Property of C₁₀H₄ClF₆N₃S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₀H₄ClF₆N₃S

There total 4 articles about C₁₀H₄ClF₆N₃S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C10H7F6N3*ClH (1309044-56-1) → C10H4ClF6N3S (1308251-18-4)

Guidance literature:

With sulfur dichloride; In acetonitrile; Reflux; Inert atmosphere;

DOI:10.1021/ic2003996

Reference yield:

C10H7F6N3 (1309044-52-7) → C10H4ClF6N3S (1308251-18-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / diethyl ether / Inert atmosphere

2: sulfur dichloride / acetonitrile / Reflux; Inert atmosphere

With hydrogenchloride; sulfur dichloride; In diethyl ether; acetonitrile;

DOI:10.1021/ic2003996

Reference yield:

4-CF3C6H4CN (455-18-5) → C10H4ClF6N3S (1308251-18-4)

Guidance literature:

Multi-step reaction with 4 steps

1.1: lithium bis(trimethylsilyl)amide diethyl etherate / diethyl ether / Inert atmosphere

1.2: Inert atmosphere

1.3: Inert atmosphere

2.1: acetonitrile / -196 - 60 °C / Inert atmosphere

3.1: hydrogenchloride / diethyl ether / Inert atmosphere

4.1: sulfur dichloride / acetonitrile / Reflux; Inert atmosphere

With hydrogenchloride; sulfur dichloride; lithium bis(trimethylsilyl)amide diethyl etherate; In diethyl ether; acetonitrile;

DOI:10.1021/ic2003996

upstream raw materials:

C₁₀H₇F₆N₃

C₁₀H₇F₆N₃*ClH

4-CF₃C₆H₄CN

4-trifluoromethylbenzamidine

Downstream raw materials:

C₁₀H₄F₆N₃S

Refernces