4-amino-5-(4-(methylthio)phenyl)-3-phenyl-1-p-tolyl-1H-pyrrol-2(5H)-one

Base Information

Chemical Name:4-amino-5-(4-(methylthio)phenyl)-3-phenyl-1-p-tolyl-1H-pyrrol-2(5H)-one
CAS No.:1381802-39-6
Molecular Formula:C₂₄H₂₂N₂OS
Molecular Weight:386.517
Hs Code.:

Synonyms:4-amino-5-(4-(methylthio)phenyl)-3-phenyl-1-p-tolyl-1H-pyrrol-2(5H)-one

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Chemical Property of 4-amino-5-(4-(methylthio)phenyl)-3-phenyl-1-p-tolyl-1H-pyrrol-2(5H)-one

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Technology Process of 4-amino-5-(4-(methylthio)phenyl)-3-phenyl-1-p-tolyl-1H-pyrrol-2(5H)-one

There total 3 articles about 4-amino-5-(4-(methylthio)phenyl)-3-phenyl-1-p-tolyl-1H-pyrrol-2(5H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1381803-64-0
C₂₄H₂₂N₂OS

: 1381802-39-6
4-amino-5-(4-(methylthio)phenyl)-3-phenyl-1-p-tolyl-1H-pyrrol-2(5H)-one

Guidance literature:: C₂₄H₂₂N₂OS; With potassium hydroxide; In ethanol; at 75 ℃; for 0.75h;

With water; In ethanol;
DOI:10.1021/jo3004309

Reference yield:

: 461443-92-5
C₁₆H₁₆N₂S

: 1381802-39-6
4-amino-5-(4-(methylthio)phenyl)-3-phenyl-1-p-tolyl-1H-pyrrol-2(5H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: 1,4-dioxane / 3 h / 20 - 110 °C

2: potassium hydroxide / ethanol / 0.75 h / 75 °C

With potassium hydroxide; In 1,4-dioxane; ethanol;
DOI:10.1021/jo3004309

Reference yield:

: 22116-68-3
C₁₅H₁₅NS

: 1381802-39-6
4-amino-5-(4-(methylthio)phenyl)-3-phenyl-1-p-tolyl-1H-pyrrol-2(5H)-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: cetyltrimethylammonim bromide / ethanol; water / 20 °C

1.2: 2 h / 60 °C

2.1: 1,4-dioxane / 3 h / 20 - 110 °C

3.1: potassium hydroxide / ethanol / 0.75 h / 75 °C

With cetyltrimethylammonim bromide; potassium hydroxide; In 1,4-dioxane; ethanol; water;
DOI:10.1021/jo3004309