Technology Process of C14H20O3Si
There total 4 articles about C14H20O3Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(E)-4-[dimethyl(phenyl)silyl]but-2-en-1-ol;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 - 20 ℃;
for 0.5h;
Inert atmosphere;
monosodium iodoacetate;
In
tetrahydrofuran;
at 20 ℃;
for 18h;
Further stages;
Inert atmosphere;
DOI:10.1021/ol201795w
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: lithium aluminium tetrahydride / diethyl ether / 18 h / 0 - 45 °C / Inert atmosphere
1.2: 0 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 - 20 °C / Inert atmosphere
2.2: 18 h / 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; n-butyllithium;
In
tetrahydrofuran; diethyl ether;
DOI:10.1021/ol201795w
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: magnesium; mercury dichloride / diethyl ether; toluene / 2.25 h / 0 - 20 °C / Inert atmosphere
1.2: 18 h / 0 - 20 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 1.33 h / -78 - 0 °C / Inert atmosphere
2.2: 4 h / 0 - 20 °C / Inert atmosphere
2.3: 20 °C / Inert atmosphere
3.1: lithium aluminium tetrahydride / diethyl ether / 18 h / 0 - 45 °C / Inert atmosphere
3.2: 0 °C / Inert atmosphere
4.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 - 20 °C / Inert atmosphere
4.2: 18 h / 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; n-butyllithium; magnesium; mercury dichloride;
In
tetrahydrofuran; diethyl ether; hexane; toluene;
DOI:10.1021/ol201795w
