3-(2,5-Dimethylpyrrol-1-yl)phenol

Base Information

Chemical Name:3-(2,5-Dimethylpyrrol-1-yl)phenol
CAS No.:97608-33-8
Molecular Formula:C₁₂H₁₃NO
Molecular Weight:187.241
Hs Code.:2933998090
DSSTox Substance ID:DTXSID00381740
Wikidata:Q82172766

Synonyms:97608-33-8;3-(2,5-Dimethyl-1-pyrrolyl)phenol;3-(2,5-dimethyl-1H-pyrrol-1-yl)phenol;3-(2,5-dimethylpyrrol-1-yl)phenol;Phenol, 3-(2,5-dimethyl-1H-pyrrol-1-yl)-;MFCD01314064;SCHEMBL14402131;DTXSID00381740;XDA60833;AC1658;NB-177;AKOS000285563;SB62447;CS-12245;SY041430;CS-0259792;FT-0718889;EN300-7423636;A917328

Suppliers and Price of 3-(2,5-Dimethylpyrrol-1-yl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(2,5-Dimethyl-1-pyrrolyl)phenol
50mg
$ 45.00

TRC
3-(2,5-Dimethyl-1-pyrrolyl)phenol
500mg
$ 175.00

Crysdot
3-(2,5-Dimethyl-1H-pyrrol-1-yl)phenol 97%
5g
$ 376.00

Chemenu
3-(2,5-Dimethyl-1-pyrrolyl)phenol 95%
5g
$ 442.00

American Custom Chemicals Corporation
3-(2,5-DIMETHYL-1H-PYRROL-1-YL)PHENOL 95.00%
1G
$ 1172.17

AK Scientific
3-(2,5-Dimethylpyrrol-1-yl)phenol
1g
$ 222.00

AK Scientific
3-(2,5-Dimethylpyrrol-1-yl)phenol
250mg
$ 141.00

Total 5 raw suppliers

Chemical Property of 3-(2,5-Dimethylpyrrol-1-yl)phenol

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:187.099714038
Heavy Atom Count:14
Complexity:185

Purity/Quality:

97% ^*data from raw suppliers

3-(2,5-Dimethyl-1-pyrrolyl)phenol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(N1C2=CC(=CC=C2)O)C
Uses 3-(2,5-Dimethyl-1-pyrrolyl)phenol is used as a reactant in the synthesis of poyrrolone antimalarials.

Technology Process of 3-(2,5-Dimethylpyrrol-1-yl)phenol

There total 1 articles about 3-(2,5-Dimethylpyrrol-1-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 110-13-4
2,5-hexanedione

: 591-27-5
m-Hydroxyaniline

: 97608-33-8
3-(2,5-dimethyl-1H-pyrrol-1-yl)phenol

Guidance literature:: With silica gel; toluene-4-sulfonic acid; In neat (no solvent); at 180 ℃; Microwave irradiation;
DOI:10.1021/jm400009c

Reference yield: 58.0%

: 97608-33-8
3-(2,5-dimethyl-1H-pyrrol-1-yl)phenol

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 878424-24-9
1-(3-hydroxyphenyl)-2,5-dimethyl-1H-pyrrole-3-carbaldehyde

Guidance literature:: N,N-dimethyl-formamide; With trichlorophosphate; at 20 ℃; for 0.25h; Inert atmosphere;

3-(2,5-dimethyl-1H-pyrrol-1-yl)phenol; at 100 ℃; for 3h; Inert atmosphere;
DOI:10.1021/jm400009c

Reference yield:

: 97608-33-8
3-(2,5-dimethyl-1H-pyrrol-1-yl)phenol

: 1428183-56-5
C₂₁H₂₂N₂O₄

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / 0.25 h / 20 °C / Inert atmosphere

1.2: 3 h / 100 °C / Inert atmosphere

2.1: potassium hydrogensulfate / ethanol / 3 h / 70 - 80 °C

With potassium hydrogensulfate; trichlorophosphate; In ethanol; 1.2: |Vilsmeier-Haack Formylation;
DOI:10.1021/jm400009c