N-Boc-5-Bromoanthranilic acid

Base Information

Chemical Name:N-Boc-5-Bromoanthranilic acid
CAS No.:306937-20-2
Molecular Formula:C12H14 Br N O4
Molecular Weight:316.151
Hs Code.:2924299090
European Community (EC) Number:630-020-0
DSSTox Substance ID:DTXSID20352336
Wikidata:Q82129411
ChEMBL ID:CHEMBL4792568
Mol file:306937-20-2.mol

Synonyms:N-Boc-5-Bromoanthranilic acid;306937-20-2;5-Bromo-2-((tert-butoxycarbonyl)amino)benzoic acid;5-bromo-2-[(2-methylpropan-2-yl)oxycarbonylamino]benzoic Acid;Benzoic acid, 5-bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]- (9CI);MFCD01619006;5-bromo-2-{[(tert-butoxy)carbonyl]amino}benzoic acid;2-(Boc-amino)-5-bromobenzoic Acid;Cambridge id 6881760;N-Boc-5-bromoanthranilicacid;SCHEMBL3490024;CHEMBL4792568;DTXSID20352336;XRMSYCMCKRUWJD-UHFFFAOYSA-N;AKOS001681779;DS-10900;SY101513;CS-0019045;FT-0647495;5-bromo-2-tert-butoxycarbonylamino-benzoic acid;EN300-198333;5-Bromo-2-((tert-butoxycarbonyl)amino)benzoicacid;A876112;5-Bromo-2-(N-tert.Butoxycarbonyl)aminobenzoic acid;5-Bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]benzoic acid;Benzoic acid, 5-bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]-;Benzoic acid,5-bromo-2-[[(1,1-dimethylethoxy)carbonyl]amino]-(9ci)

Suppliers and Price of N-Boc-5-Bromoanthranilic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Boc-5-bromoanthranilicAcid
50mg
$ 60.00

SynQuest Laboratories
2-Amino-5-bromobenzoic acid, N-Boc protected
1 g
$ 176.00

SynQuest Laboratories
2-Amino-5-bromobenzoic acid, N-Boc protected
5 g
$ 320.00

Matrix Scientific
Boc-2-amino-5-bromobenzoic acid
5g
$ 785.00

Matrix Scientific
Boc-2-amino-5-bromobenzoic acid
1g
$ 212.00

Chemenu
Boc-2-amino-5-bromobenzoicacid 95%
5g
$ 183.00

Chemenu
Boc-2-amino-5-bromobenzoicacid 95%
10g
$ 276.00

Biosynth Carbosynth
N-Boc-5-Bromoanthranilic acid
5 g
$ 302.00

Biosynth Carbosynth
N-Boc-5-Bromoanthranilic acid
2 g
$ 151.00

Biosynth Carbosynth
N-Boc-5-Bromoanthranilic acid
1 g
$ 87.00

Total 20 raw suppliers

Chemical Property of N-Boc-5-Bromoanthranilic acid

Chemical Property:

Vapor Pressure:4.91E-06mmHg at 25°C
Refractive Index:1.598
Boiling Point:367.1°C at 760 mmHg
PKA:3.31±0.36(Predicted)
Flash Point:175.8°C
PSA：75.63000
Density:1.526g/cm³
LogP:3.56730
Storage Temp.:2-8°C
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:315.01062
Heavy Atom Count:18
Complexity:327

Purity/Quality:

97% ^*data from raw suppliers

N-Boc-5-bromoanthranilicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=C(C=C(C=C1)Br)C(=O)O

Technology Process of N-Boc-5-Bromoanthranilic acid

There total 3 articles about N-Boc-5-Bromoanthranilic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 5794-88-7
5-Bromo-2-aminobenzoic acid

: 306937-20-2
5-bromo-2-((tert-butoxycarbonyl)amino)benzoic acid

Guidance literature:: With sodium carbonate; In dichloromethane; at 20 - 40 ℃; for 25h;
DOI:10.1002/ejoc.200700142

Reference yield: 28.0%

: 24424-99-5
di-tert-butyl dicarbonate

: C₈H₆BrNO₄

: 306937-20-2
5-bromo-2-((tert-butoxycarbonyl)amino)benzoic acid

Guidance literature:: With dmap; triethylamine; In acetonitrile; at 40 ℃; for 0.25h; Microwave irradiation;
DOI:10.1016/j.ejmech.2020.112440

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 306937-20-2
5-bromo-2-((tert-butoxycarbonyl)amino)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / [bmim]Br₃ / CH₂Cl₂ / 0.67 h / 20 °C

2: 60 percent / Na₂CO₃ / CH₂Cl₂ / 25 h / 20 - 40 °C

With sodium carbonate; In dichloromethane;
DOI:10.1002/ejoc.200700142