3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate

Base Information

Chemical Name:3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate
CAS No.:1346703-12-5
Molecular Formula:C₂HF₃O₂*C₁₃H₂₀N₂O
Molecular Weight:334.339
Hs Code.:

Synonyms:3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate

Suppliers and Price of 3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate

There total 2 articles about 3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 4-cyclohexyl-6-methyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile

: 76-05-1
trifluoroacetic acid

: 1346703-12-5
3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate

Guidance literature:: 4-cyclohexyl-6-methyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile; With sodium tetrahydroborate; iodine; In tetrahydrofuran; for 3.5h; Cooling with ice; Reflux;

trifluoroacetic acid;

Reference yield:

: 2043-61-0
cyclohexanecarbaldehyde

: 1346703-12-5
3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: chromium dichloride / tetrahydrofuran / 2 h / Reflux

1.2: 1.5 h / 20 °C

2.1: sodium tetrahydroborate; iodine / tetrahydrofuran / 3.5 h / Cooling with ice; Reflux

With chromium dichloride; sodium tetrahydroborate; iodine; In tetrahydrofuran;

Reference yield: 74.0%

: 1346702-54-2
6-bromo-1-(1-methylethyl)-1H-indazole-4-carboxylic acid

: 1346703-12-5
3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate

: 1346703-11-4
6-bromo-N-((4-cyclohexyl-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-1H-indazole-4-carboxamide

Guidance literature:: 6-bromo-1-(1-methylethyl)-1H-indazole-4-carboxylic acid; 3-(aminomethyl)-4-cyclohexyl-6-methyl-2(1H)-pyridinone trifluoroacetate; With 4-methyl-morpholine; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dimethyl sulfoxide; at 20 ℃; Inert atmosphere;

With potassium carbonate; In water; dimethyl sulfoxide; at 20 ℃; for 1h; pH=~ 8 - ~ 9; Product distribution / selectivity; Cooling with ice;