Technology Process of 2-O,5-O-dibenzyl-10,11-epoxy-10,11-dihydrocurcuhydroquinone
There total 3 articles about 2-O,5-O-dibenzyl-10,11-epoxy-10,11-dihydrocurcuhydroquinone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium acetate; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane;
at 20 ℃;
for 2h;
DOI:10.1016/j.bmc.2012.09.042
- Guidance literature:
-
Multi-step reaction with 5 steps
1: trifluoroborane diethyl ether / 3 h / 120 °C
2: potassium carbonate / 1,2-dimethoxyethane / 12 h / 80 °C
3: iodine; magnesium / tetrahydrofuran / Inert atmosphere
4: triethylsilane; trifluoroborane diethyl ether / dichloromethane / 12 h / -78 - -55 °C / Inert atmosphere
5: sodium acetate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 20 °C
With
triethylsilane; iodine; sodium acetate; trifluoroborane diethyl ether; potassium carbonate; magnesium; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane;
DOI:10.1016/j.bmc.2012.09.042
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium carbonate / 1,2-dimethoxyethane / 12 h / 80 °C
2: iodine; magnesium / tetrahydrofuran / Inert atmosphere
3: triethylsilane; trifluoroborane diethyl ether / dichloromethane / 12 h / -78 - -55 °C / Inert atmosphere
4: sodium acetate; 3-chloro-benzenecarboperoxoic acid / dichloromethane / 2 h / 20 °C
With
triethylsilane; iodine; sodium acetate; trifluoroborane diethyl ether; potassium carbonate; magnesium; 3-chloro-benzenecarboperoxoic acid;
In
tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane;
DOI:10.1016/j.bmc.2012.09.042
