3-(2-Pyridyl)isoquinoline

Base Information

Chemical Name:3-(2-Pyridyl)isoquinoline
CAS No.:58814-67-8
Molecular Formula:C₁₄H₁₀N₂
Molecular Weight:206.247
Hs Code.:
DSSTox Substance ID:DTXSID00877390
Nikkaji Number:J1.580.551J

Synonyms:58814-67-8;3-(2-Pyridyl)isoquinoline;3-(2-pyridyl)-isoquinoline;SCHEMBL936185;DTXSID00877390;Isoquinoline, 3-(2-pyridinyl)-

Suppliers and Price of 3-(2-Pyridyl)isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 3-(2-Pyridyl)isoquinoline

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:206.084398327
Heavy Atom Count:16
Complexity:229

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C=NC(=CC2=C1)C3=CC=CC=N3

Technology Process of 3-(2-Pyridyl)isoquinoline

There total 1 articles about 3-(2-Pyridyl)isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3731-51-9
2-(Aminomethyl)pyridine

: 85-44-9
phthalic anhydride

: 58814-67-8
3-(pyridine-2-yl)isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 2 h / 120 °C / Inert atmosphere; Schlenk technique

2: potassium trimethylsilonate; diethoxymethylane / diethylene glycol dimethyl ether / 6 h / 120 °C / Inert atmosphere; Schlenk technique; Sealed tube

With diethoxymethylane; potassium trimethylsilonate; acetic acid; In diethylene glycol dimethyl ether;
DOI:10.1021/acs.orglett.8b02287

Reference yield: 93.0%

: 17084-13-8
potassium hexafluorophosphate

: 32648-33-2
trans-bis((diphenylthio)ethane)dichlororuthenium(II)

: 58814-67-8
3-(pyridine-2-yl)isoquinoline

: [Ru(II)((diphenylthio)ethane)(pyridylquinoline)](PF₆)2

Guidance literature:: In not given; Ru complex with four molar excess of (C5NH4)(C9H6N) refluxed (2-3 h); solvent removed in vac.; solid treated with aq. soln. of KPF6; recrystd. from acetone/Et2O; solid collected; washed with hexane; elem. anal.;
DOI:10.1023/A:1021158931775