4-Amino-2-methylthio-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidin

Base Information

Chemical Name:4-Amino-2-methylthio-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidin
CAS No.:78153-61-4
Molecular Formula:C₃₃H₃₄N₄O₄S
Molecular Weight:582.723
Hs Code.:

Synonyms:4-Amino-2-methylthio-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidin

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Amino-2-methylthio-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidin

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of 4-Amino-2-methylthio-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidin

There total 2 articles about 4-Amino-2-methylthio-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 70613-79-5
2,3,5-tri-O-benzyl-D-arabinofuranosyl bromide

: 57564-92-8
4-Amino-2-methylthio-7H-pyrrolo-<2,3-d>pyrimidin

: 74895-44-6
4-Amino-2-methylthio-7-(2,3,5-tri-O-benzyl-β-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidin

: 78153-61-4
4-Amino-2-methylthio-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidin

Guidance literature:: With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In 1,2-dimethoxyethane; dichloromethane; for 0.25h;

Reference yield:

: 52522-49-3
2,3,5-tri-O-benzyl-1-(4-nitrobenzoyloxy)-D-arabinofuranose

: 78153-61-4
4-Amino-2-methylthio-7-(2,3,5-tri-O-benzyl-α-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidin

Guidance literature:: Multi-step reaction with 2 steps

1: HBr / CH₂Cl₂

2: 14 percent / benzyltriethylammonium chloride, 50percent aq. NaOH / CH₂Cl₂ / 0.25 h

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; hydrogen bromide; In dichloromethane;