(E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal

Base Information

Chemical Name:(E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal
CAS No.:152901-69-4
Molecular Formula:C₃₂H₄₀O₄Si
Molecular Weight:516.753
Hs Code.:

Synonyms:(E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal

Suppliers and Price of (E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal

There total 7 articles about (E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 152901-61-6
(E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-en-1-ol

: 152901-69-4
(E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal

Guidance literature:: With oxalyl dichloride; dimethyl sulfoxide; triethylamine; In dichloromethane;
DOI:10.1016/S0040-4039(00)73848-2

Reference yield:

: 1888-89-7,74892-53-8,131722-62-8,74892-51-6
(2S,5S)-1,5-hexadiene diepoxide

: 152901-69-4
(E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) Vitride, 2.) DMAP / 1.) THF

2: 1.) LDA / 1.) THF

3: 1.) mCPBA, 2.) pyridine / 1.) CH₂Cl₂, -30 deg C, 1 h, 2.) toluene, reflux

4: i-PrNEt₂ / CH₂Cl₂ / Heating

5: 79 percent / DIBAH-H / CH₂Cl₂; toluene / -78 °C

6: 96 percent / (COCl)2, DMSO, Et₃N / CH₂Cl₂

With pyridine; dmap; oxalyl dichloride; N,N-diethyl-N-isopropylamine; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; sodium bis(2-methoxyethoxy)aluminium dihydride; lithium diisopropyl amide; In dichloromethane; toluene;
DOI:10.1016/S0040-4039(00)73848-2

Reference yield:

: 152901-58-1
tert-Butyl-((R)-1-methyl-3-(S)-oxiranyl-propoxy)-diphenyl-silane

: 152901-69-4
(E)-(4S,7R)-4-Benzyloxymethoxy-7-(tert-butyl-diphenyl-silanyloxy)-oct-2-enal

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) LDA / 1.) THF

2: 1.) mCPBA, 2.) pyridine / 1.) CH₂Cl₂, -30 deg C, 1 h, 2.) toluene, reflux

3: i-PrNEt₂ / CH₂Cl₂ / Heating

4: 79 percent / DIBAH-H / CH₂Cl₂; toluene / -78 °C

5: 96 percent / (COCl)2, DMSO, Et₃N / CH₂Cl₂

With pyridine; oxalyl dichloride; N,N-diethyl-N-isopropylamine; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; lithium diisopropyl amide; In dichloromethane; toluene;
DOI:10.1016/S0040-4039(00)73848-2