5-Benzyl-1,3,4-oxadiazol-2-amine

Base Information

Chemical Name:5-Benzyl-1,3,4-oxadiazol-2-amine
CAS No.:31803-00-6
Molecular Formula:C9H9 N3 O
Molecular Weight:175.19
Hs Code.:2934999090
European Community (EC) Number:671-501-5
DSSTox Substance ID:DTXSID90373457
Nikkaji Number:J1.584.243A
Wikidata:Q82161634
Mol file:31803-00-6.mol

Synonyms:5-benzyl-1,3,4-oxadiazol-2-amine;31803-00-6;5-Benzyl-1,3,4-oxadiazol-2-ylamine;1,3,4-Oxadiazol-2-amine, 5-(phenylmethyl)-;Oprea1_587959;SCHEMBL5915148;DTXSID90373457;UEHXUDSFIIVUNO-UHFFFAOYSA-N;2-amino-5-benzyl-1,3,4-oxadiazol;AOD100695;MFCD00159750;5-Benzyl-1,3,4-oxadiazole-2-amine;AKOS000124320;AB04199;CCG-309988;FS-1250;5-Benzyl-[1,3,4]oxadiazol-2-ylamine;FT-0638997;EN300-181889;5-benzyl-1,3,4-oxadiazol-2-ylamine, AldrichCPR;A821006;F2182-0018

Suppliers and Price of 5-Benzyl-1,3,4-oxadiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Benzyl-1,3,4-oxadiazol-2-amine
50mg
$ 60.00

Matrix Scientific
5-Benzyl-1,3,4-oxadiazol-2-amine 95%+
1g
$ 306.00

Matrix Scientific
5-Benzyl-1,3,4-oxadiazol-2-amine 95%+
5g
$ 1010.00

Matrix Scientific
5-Benzyl-1,3,4-oxadiazol-2-amine 95%+
2.500g
$ 666.00

Crysdot
5-Benzyl-1,3,4-oxadiazol-2-amine 97%
25g
$ 574.00

Biosynth Carbosynth
5-Benzyl-1,3,4-oxadiazol-2-ylamine
5 g
$ 450.00

Biosynth Carbosynth
5-Benzyl-1,3,4-oxadiazol-2-ylamine
10 g
$ 850.00

Biosynth Carbosynth
5-Benzyl-1,3,4-oxadiazol-2-ylamine
2 g
$ 280.00

Biosynth Carbosynth
5-Benzyl-1,3,4-oxadiazol-2-ylamine
1 g
$ 150.00

Biosynth Carbosynth
5-Benzyl-1,3,4-oxadiazol-2-ylamine
500 mg
$ 100.00

Total 16 raw suppliers

Chemical Property of 5-Benzyl-1,3,4-oxadiazol-2-amine

Chemical Property:

Vapor Pressure:2.44E-05mmHg at 25°C
Melting Point:161-163°C
Refractive Index:1.604
Boiling Point:359.1°C at 760 mmHg
PKA:-0.50±0.13(Predicted)
Flash Point:170.9°C
PSA：64.94000
Density:1.248g/cm³
LogP:1.82380
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:175.074561919
Heavy Atom Count:13
Complexity:159

Purity/Quality:

97% ^*data from raw suppliers

5-Benzyl-1,3,4-oxadiazol-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC2=NN=C(O2)N
Uses 5-benzyl-1,3,4-oxadiazol-2-amine is a useful chemical for the synthesis process of 6,?7-?dimethoxy quinazoline derivatives for the purpose as VEGFR-?2 tyrosine kinase inhibitors as potential anticancer agents.

Technology Process of 5-Benzyl-1,3,4-oxadiazol-2-amine

There total 9 articles about 5-Benzyl-1,3,4-oxadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 506-68-3
bromocyane

: 937-39-3
2-phenylacetylhydrazine

: 31803-00-6
5-benzyl-2-amino-1,3,4-oxadiazole

Guidance literature:: In ethanol; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.tetlet.2019.04.022

Reference yield: 80.0%

: 1722-94-7
phenylacetaldehyde semicarbazone

: 31803-00-6
5-benzyl-2-amino-1,3,4-oxadiazole

Guidance literature:: phenylacetaldehyde semicarbazone; With N-Bromosuccinimide; acetic acid; at 0 - 20 ℃; for 0.5h;

With sodium acetate; at 25 ℃; for 1h;
DOI:10.1080/00397911.2017.1324626

Reference yield: 65.0%

: 29313-28-8
1-phenylacetyl-thiosemicarbazide

: 31803-00-6
5-benzyl-2-amino-1,3,4-oxadiazole

Guidance literature:: With Oxone; iodine; sodium hydroxide; In water; isopropyl alcohol; at 0 - 20 ℃; for 0.5h;
DOI:10.3184/174751912X13551638283701