N-(trifluoroacetyl)-1-(2,5-dimethoxy-4-hydrocinnamoylphenyl)-2-aminopropane

Base Information

Chemical Name:N-(trifluoroacetyl)-1-(2,5-dimethoxy-4-hydrocinnamoylphenyl)-2-aminopropane
CAS No.:125926-55-8
Molecular Formula:C₂₂H₂₄F₃NO₄
Molecular Weight:423.432
Hs Code.:

Synonyms:N-(trifluoroacetyl)-1-(2,5-dimethoxy-4-hydrocinnamoylphenyl)-2-aminopropane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(trifluoroacetyl)-1-(2,5-dimethoxy-4-hydrocinnamoylphenyl)-2-aminopropane

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Technology Process of N-(trifluoroacetyl)-1-(2,5-dimethoxy-4-hydrocinnamoylphenyl)-2-aminopropane

There total 2 articles about N-(trifluoroacetyl)-1-(2,5-dimethoxy-4-hydrocinnamoylphenyl)-2-aminopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 79315-43-8
(+/-)-N-[2-(2,5-dimethoxyphenyl)-1-methylethyl]-2,2,2-trifluoroacetamide

: 645-45-4
hydrocinnamic acid chloride

: 125926-55-8
N-(trifluoroacetyl)-1-(2,5-dimethoxy-4-hydrocinnamoylphenyl)-2-aminopropane

Guidance literature:: With titanium tetrachloride; In dichloromethane; 1.) -30 deg C, 30 min, 2.) RT, 3 d;
DOI:10.1021/jm00165a023

Reference yield:

: 2801-68-5
2,5-dimethoxyphenylisopropylamine

: 125926-55-8
N-(trifluoroacetyl)-1-(2,5-dimethoxy-4-hydrocinnamoylphenyl)-2-aminopropane

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / 2 h / Ambient temperature

2: 44 percent / titanium tetrachloride / CH₂Cl₂ / 1.) -30 deg C, 30 min, 2.) RT, 3 d

With titanium tetrachloride; In dichloromethane;
DOI:10.1021/jm00165a023