1,2-Cyclopentanediol, 3-amino-5-(hydroxymethyl)-, (1S,2S,3R,5R)- (9CI)

Base Information

Chemical Name:1,2-Cyclopentanediol, 3-amino-5-(hydroxymethyl)-, (1S,2S,3R,5R)- (9CI)
CAS No.:305384-32-1
Molecular Formula:C₆H₁₃NO₃
Molecular Weight:147.174
Hs Code.:
Mol file:305384-32-1.mol

Synonyms:1,2-Cyclopentanediol, 3-amino-5-(hydroxymethyl)-, (1S,2S,3R,5R)- (9CI)

Suppliers and Price of 1,2-Cyclopentanediol, 3-amino-5-(hydroxymethyl)-, (1S,2S,3R,5R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,2-Cyclopentanediol, 3-amino-5-(hydroxymethyl)-, (1S,2S,3R,5R)- (9CI)

Chemical Property:

Boiling Point:300.9±42.0 °C(Predicted)
PKA:14.24±0.70(Predicted)
PSA：86.71000
Density:1.352±0.06 g/cm3(Predicted)
LogP:-1.25200

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 1,2-Cyclopentanediol, 3-amino-5-(hydroxymethyl)-, (1S,2S,3R,5R)- (9CI)

There total 184 articles about 1,2-Cyclopentanediol, 3-amino-5-(hydroxymethyl)-, (1S,2S,3R,5R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 445469-23-8
(1R,2S,3R,4R)-[2,3-bis-(tert-butyldimethylsilanyloxy)-4-hydroxymethyl-cyclopentyl]carbamic acid tert-butyl ester

: 85026-59-1,305384-32-1,780705-82-0
(-)-(1R,2R,3S,4R)-4-amino-2,3-dihydroxy-1-(hydroxymethyl)cyclopentane

Guidance literature:: (1R,2S,3R,4R)-[2,3-bis-(tert-butyldimethylsilanyloxy)-4-hydroxymethyl-cyclopentyl]carbamic acid tert-butyl ester; With hydrogenchloride; In tetrahydrofuran; methanol; water; at 20 ℃; for 6h;

With DOWEX (H⁺ form); Further stages.;
DOI:10.1021/jo0257905

Reference yield: 98.0%

: (1R,2S,3R,5R)-3-Azido-5-hydroxymethyl-cyclopentane-1,2-diol

: 62138-01-6,305384-32-1,780705-82-0
(+/-)-(1α,2α,3β,5β)-3-amino-5-(hydroxymethyl)-1,2-cyclopentanediol

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; chloroform;

Reference yield: 95.0%

: 445469-22-7
(1R,2S,3S,4R)-[2,3-bis-(tert-butyldimethylsilanyloxy)-4-hydroxymethylcyclopentyl]carbamic acid tert-butyl ester

: 305384-32-1,780705-82-0
(1S,2S,3R,5R)-3-amino-5-(hydroxymethyl)cyclopentane-1,2-diol

Guidance literature:: (1R,2S,3S,4R)-[2,3-bis-(tert-butyldimethylsilanyloxy)-4-hydroxymethylcyclopentyl]carbamic acid tert-butyl ester; With hydrogenchloride; In tetrahydrofuran; methanol; water; at 20 ℃; for 6h;

With DOWEX (H⁺ form); Further stages.;
DOI:10.1021/jo0257905