2-(4-Bromobutoxy)tetrahydro-2H-pyran

Base Information

• Chemical Name: 2-(4-Bromobutoxy)tetrahydro-2H-pyran
• CAS No.: 31608-22-7
• Molecular Formula: C9H17 Br O2
• Molecular Weight: 237.137
• Hs Code.: 2932999099
• Mol file: 31608-22-7.mol

Synonyms:1-Bromo-4-[(tetrahydro-2H-pyran-2-yl)oxy]butane;2-(4-Bromobutoxy)tetrahydro-2H-pyran; 4-Bromobutyl tetrahydropyranyl ether;4-[(Tetrahydropyranyl)oxy]butyl bromide

Chemical Property of 2-(4-Bromobutoxy)tetrahydro-2H-pyran

Chemical Property:

• Vapor Pressure: 0.00498mmHg at 25°C
• Refractive Index: 1.481
• Boiling Point: 284.9°C at 760 mmHg
• Flash Point: 118.3°C
• PSA: 18.46000
• Density: 1.29
• LogP: 2.70470
• Storage Temp.: Freezer

Purity/Quality:

≥99% ^*data from raw suppliers

2-(4-Bromobutoxy)oxane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-Bromobutoxy)tetrahydro-2H-pyran

There total 7 articles about 2-(4-Bromobutoxy)tetrahydro-2H-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3,4-dihydro-2H-pyran (110-87-2) + 4-Bromo-1-butanol (33036-62-3) → 4-bromo-1-(2-tetrahydropyranyloxy)butane (31608-22-7)

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; at 20 ℃; for 24h;

Reference yield: 90.0%

4-(tetrahydropyran-2-yloxy)butan-1-ol (51326-51-3) → 4-bromo-1-(2-tetrahydropyranyloxy)butane (31608-22-7)

Guidance literature:

With tetrabutylammomium bromide; (chloro-phenylthio-methylene)dimethylammonium chloride; triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1016/S0040-4039(00)00940-0

Reference yield: 86.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + 3,4-dihydro-2H-pyran (110-87-2) → 4-bromo-1-(2-tetrahydropyranyloxy)butane (31608-22-7)

Guidance literature:

tetrahydrofuran; 3,4-dihydro-2H-pyran; With trimethylsilyl bromide; In dichloromethane; for 16h; Heating;

With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 4h; Further stages.;

DOI:10.1021/jm990340z

upstream raw materials:

3,4-dihydro-2H-pyran

4-Bromobutyl acetate

4-Bromo-1-butanol

4-(tetrahydropyran-2-yloxy)butan-1-ol

Downstream raw materials:

hept-5-yn-1-ol

2-(8-bromooctyloxy)tetrahydropyran

(E)-5-Decenylbromid

1,7-dioxaspiro[5.5]undecane