Technology Process of C28H26ClF3N6O4
There total 3 articles about C28H26ClF3N6O4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C11H9F2N3O; clinafloxacin;
With
sodium hydrogencarbonate;
In
ethanol;
at 70 ℃;
With
formic acid;
In
ethanol;
at 20 ℃;
pH=5.5 - 6.5;
DOI:10.1016/j.bmcl.2012.07.064
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydroxide / toluene / 60 °C
2.1: sodium hydrogencarbonate / ethanol / 70 °C
2.2: 20 °C / pH 5.5 - 6.5
With
sodium hydrogencarbonate; sodium hydroxide;
In
ethanol; toluene;
DOI:10.1016/j.bmcl.2012.07.064
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: aluminum (III) chloride / dichloromethane / 20 °C
2.1: potassium carbonate / acetonitrile / 20 - 80 °C
3.1: sodium hydroxide / toluene / 60 °C
4.1: sodium hydrogencarbonate / ethanol / 70 °C
4.2: 20 °C / pH 5.5 - 6.5
With
aluminum (III) chloride; sodium hydrogencarbonate; potassium carbonate; sodium hydroxide;
In
ethanol; dichloromethane; toluene; acetonitrile;
DOI:10.1016/j.bmcl.2012.07.064