(+)-6-methyl-1-<(S)-1-phenylethylimino>-1,2,3,4-tetrahydrocarbazole

Base Information

• Chemical Name: (+)-6-methyl-1-<(S)-1-phenylethylimino>-1,2,3,4-tetrahydrocarbazole
• CAS No.: 206128-56-5
• Molecular Formula: C₂₁H₂₂N₂
• Molecular Weight: 302.419
• Mol file: 206128-56-5.mol

Synonyms:(+)-6-methyl-1-<(S)-1-phenylethylimino>-1,2,3,4-tetrahydrocarbazole

Chemical Property of (+)-6-methyl-1-<(S)-1-phenylethylimino>-1,2,3,4-tetrahydrocarbazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-6-methyl-1-<(S)-1-phenylethylimino>-1,2,3,4-tetrahydrocarbazole

There total 1 articles about (+)-6-methyl-1-<(S)-1-phenylethylimino>-1,2,3,4-tetrahydrocarbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one (3449-48-7,812649-03-9) + (R)-1-phenyl-ethyl-amine (3886-69-9) → (+)-6-methyl-1-<(S)-1-phenylethylimino>-1,2,3,4-tetrahydrocarbazole (206128-56-5)

Guidance literature:

With toluene-4-sulfonic acid; In xylene; for 5h; Heating;

DOI:10.1007/BF00772896

Reference yield: 82.0%

(+)-6-methyl-1-<(S)-1-phenylethylimino>-1,2,3,4-tetrahydrocarbazole (206128-56-5) → (-)-6-methyl-1-<(S)-1-phenylethylamino>-1,2,3,4-tetrahydrocarbazole

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 4h;

DOI:10.1007/BF00772896

Reference yield:

(+)-6-methyl-1-<(S)-1-phenylethylimino>-1,2,3,4-tetrahydrocarbazole (206128-56-5) → (+)-8-methyl-3-<(S)-1-phenylethyl>-2,3,3a,4,5,6-hexahydro-1N-pyrazino<3,2,1-jk>carbazole

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / NaBH₄ / ethanol / 4 h / 20 °C

2: 1.) NaH / 1.) DMSO, RT, 2 h, 2.) DMSO, 2.5 h

With sodium tetrahydroborate; sodium hydride; In ethanol;

DOI:10.1007/BF00772896

upstream raw materials:

6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-one

(R)-1-phenyl-ethyl-amine

Downstream raw materials:

(+)-9-carbomethoxymethyl-6-methyl-1-<(S)-1-phenylethylamino>-1,2,3,4-tetrahydrocarbazole

(-)-9-carbomethoxymethyl-6-methyl-1-<(S)-1-phenylethylamino>-1,2,3,4-tetrahydrocarbazole