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Technology Process of 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-(5-quinolinyl)-2-propenamide

2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-(5-quinolinyl)-2-propenamide

Base Information
  • Chemical Name:2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-(5-quinolinyl)-2-propenamide
  • CAS No.:304896-28-4
  • Molecular Formula:C23H13 Cl2 N3 O2
  • Molecular Weight:434.281
  • Hs Code.:
  • DSSTox Substance ID:DTXSID80184559
  • Wikidata:Q27166409
  • Mol file:304896-28-4.mol
2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-(5-quinolinyl)-2-propenamide

Synonyms:2-Cyano-3-(5-(2,5-dichlorophenyl)-2-furanyl)-N-5-quinolinyl-2-propenamide;AGK2 compound;AGK2 SIRT2 inhibitor

Suppliers and Price of 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-(5-quinolinyl)-2-propenamide
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • AGK 2
  • 10mg
  • $ 466.00
  • TRC
  • AGK2
  • 5mg
  • $ 90.00
  • TRC
  • AGK2
  • 100mg
  • $ 925.00
  • TCI Chemical
  • AGK-2 >97.0%(HPLC)
  • 100mg
  • $ 834.00
  • TCI Chemical
  • AGK-2 >97.0%(HPLC)
  • 5mg
  • $ 102.00
  • TCI Chemical
  • AGK-2 >97.0%(HPLC)
  • 25mg
  • $ 304.00
  • Sigma-Aldrich
  • AGK2 ≥97% (HPLC), powder
  • 5mg
  • $ 132.00
  • Sigma-Aldrich
  • SIRT2 Inhibitor, AGK2
  • 5mg
  • $ 161.87
  • Sigma-Aldrich
  • AGK2 ≥97% (HPLC), powder
  • 25mg
  • $ 523.00
  • DC Chemicals
  • AGK2 >98%
  • 100 mg
  • $ 450.00
Total 24 raw suppliers
Chemical Property of 2-cyano-3-[5-(2,5-dichlorophenyl)-2-furanyl]-N-(5-quinolinyl)-2-propenamide
Chemical Property:
  • Boiling Point:675.1±55.0 °C(Predicted) 
  • PKA:8.87±0.43(Predicted) 
  • PSA：78.92000 
  • Density:1.445±0.06 g/cm3(Predicted) 
  • LogP:6.42028 
  • Storage Temp.:Room temp 
  • Solubility.:DMSO: soluble2mg/mL, clear (warmed) 
  • XLogP3:5.9
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:4
  • Rotatable Bond Count:4
  • Exact Mass:433.0384821
  • Heavy Atom Count:30
  • Complexity:706
Purity/Quality:

99%, *data from raw suppliers

AGK 2 *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes:Xi 
  • Statements: 36 
  • Safety Statements: 26 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:C1=CC2=C(C=CC=N2)C(=C1)NC(=O)C(=CC3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)C#N
  • Uses AGK2 is a SIRT2 inhibitor. AGK2 has been used in a study to determine that SIRT2 inhibition induces cell death and decreases the intracellular ATP level. AGK2 also rescues dopamine neurons from α-synuclein toxicity in Parkinson′s disease models.
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Total 8 Pictures about this product