4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone hydrochloride

Base Information

Chemical Name:4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone hydrochloride
CAS No.:939825-21-5
Molecular Formula:C₁₃H₁₃FN₂O
Molecular Weight:232.257
Hs Code.:
ChEMBL ID:CHEMBL1190702
DSSTox Substance ID:DTXSID301227195

Synonyms:CHEMBL541386;SCHEMBL410653;CHEMBL1190702;DTXSID301227195;4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone hydrochloride;BDBM50207206;939825-21-5;4-(4-fluoro-phenyl)-1-imidazol-1-yl-butan-2-one;4-(4-fluorophenyl)-1-(1h-imidazol-1-yl)-2-butanone

Suppliers and Price of 4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone hydrochloride

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:232.10119120
Heavy Atom Count:17
Complexity:252

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1CCC(=O)CN2C=CN=C2)F

Technology Process of 4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone hydrochloride

There total 4 articles about 4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 288-32-4
1H-imidazole

: 939825-18-0
1-bromo-4-(4-fluorophenyl)-2-butanone

: 939825-21-5
4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 1h;
DOI:10.1016/j.bmc.2007.02.034

Reference yield: 66.0%

: 939825-21-5
4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone

Guidance literature:

Reference yield:

: 63416-61-5
4-(4-fluorophenyl)-2-butanone

: 939825-21-5
4-(4-fluorophenyl)-1-(1H-imidazol-1-yl)-2-butanone

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / bromine / methanol / 2 h / 20 °C

2: 66 percent / dimethylformamide / 1 h / 20 °C

With bromine; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2007.02.034