SPLA2 INHIBITOR

Base Information

• Chemical Name: SPLA2 INHIBITOR
• CAS No.: 393569-31-8
• Molecular Formula: C₃₁H₃₇NO₄
• Molecular Weight: 487.639
• Mol file: 393569-31-8.mol

Synonyms:(S)-5-(4-Benzyloxyphenyl)-4-((7-phenylheptanoyl)amino)pentanoic acid;KH 064;

Chemical Property of SPLA2 INHIBITOR

Chemical Property:

• Vapor Pressure: 8.2E-22mmHg at 25°C
• Melting Point: 133-135 °C
• Refractive Index: 1.573
• Boiling Point: 720.905 °C at 760 mmHg
• PKA: 4.57±0.10(Predicted)
• Flash Point: 389.79 °C
• Density: 1.124 g/cm³
• Storage Temp.: 2-8°C
• Solubility.: DMSO: >5 mg/mL, freely soluble

Purity/Quality:

99% ^*data from raw suppliers

sPLA2 inhibitor ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Uses: sPLA2 inhibitor protects against intestinal reperfusion injury which was evident through biological studies in rats.

Technology Process of SPLA2 INHIBITOR

There total 2 articles about SPLA2 INHIBITOR which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(RS)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid methyl ester (393569-58-9) → (RS)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid (393569-67-0,393569-31-8)

Guidance literature:

With sodium hydroxide; In MeOH-THF;

Reference yield:

(S)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid methyl ester (393569-33-0) → (S)-5-(4-benzyloxyphenyl)-4-[(7-phenylheptanoyl)amino]pentanoic acid (393569-31-8)

Guidance literature:

With sodium hydroxide; In MeOH-THF;

upstream raw materials:

(S)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid methyl ester

(RS)-5-(4-Benzyloxy-phenyl)-4-(7-phenyl-heptanoylamino)-pentanoic acid methyl ester

Refernces