Ethanone, 1-[(2R,6R)-6-ethyl-3,6-dihydro-5-methyl-2H-pyran-2-yl]- (9CI)

Base Information

• Chemical Name: Ethanone, 1-[(2R,6R)-6-ethyl-3,6-dihydro-5-methyl-2H-pyran-2-yl]- (9CI)
• CAS No.: 393530-60-4
• Molecular Formula: C10H16 O2
• Molecular Weight: 168.236
• Mol file: 393530-60-4.mol

Synonyms:Ethanone, 1-[(2R,6R)-6-ethyl-3,6-dihydro-5-methyl-2H-pyran-2-yl]- (9CI)

Chemical Property of Ethanone, 1-[(2R,6R)-6-ethyl-3,6-dihydro-5-methyl-2H-pyran-2-yl]- (9CI)

Chemical Property:

• PSA: 26.30000
• LogP: 2.08920

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanone, 1-[(2R,6R)-6-ethyl-3,6-dihydro-5-methyl-2H-pyran-2-yl]- (9CI)

There total 21 articles about Ethanone, 1-[(2R,6R)-6-ethyl-3,6-dihydro-5-methyl-2H-pyran-2-yl]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(1S)-1-[(2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-2-pyranyl]ethan-1-ol (863895-02-7) → 1-[(2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-2-pyranyl]-1-ethanone (393530-60-4)

Guidance literature:

With sodium hydrogencarbonate; Dess-Martin periodane; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1039/d1ob00883h

Reference yield: 83.0%

1-((2S,6R)-6-Ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)-ethanone (863895-04-9) → 1-[(2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-2-pyranyl]-1-ethanone (393530-60-4)

Guidance literature:

With potassium carbonate; In benzene;

DOI:10.1016/j.tetlet.2005.06.040

Reference yield: 60.0%

(S)-1-((2R,6R)-6-Ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)-ethane-1,2-diol → 1-[(2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-2-pyranyl]-1-ethanone (393530-60-4)

Guidance literature:

With N-methyl-2-indolinone; tetrapropylammonium perruthennate; 4 A molecular sieve; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/S0040-4020(03)00370-3

upstream raw materials:

1-((2S,6R)-6-Ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)-ethanone

(1S)-1-[(2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-2-pyranyl]ethan-1-ol

1-(tert-butyl)-1,1-dimethylsilyl (1S)-1-[(2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-2-pyranyl]ethyl ether

tert-butyl[((1S,2R)-2-[(1R)-1-ethyl-2-methyl-2-propenyl]oxy-1-methyl-4-pentenyl)oxy]dimethylsilane

Downstream raw materials:

[2R,6R,2(2'R)]-2-[2'-hydroxy-3'-penten-2'(Z)-yl]-5-methyl-6-ethyl-3,6-dihydropyran

C₂₆H₄₄O₅SiS

5-(((S,E)-4-((2R,6R)-6-ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)-2-methylpent-3-en-1-yl)sulfonyl)-1-phenyl-1H-tetrazole

[6-(2-{2-[2-benzenesulfonyl-5-(6-ethyl-5-methyl-3,6-dihydro-2H-pyran-2-yl)-1-hydroxy-3-methyl-hex-4-enyl]-3-methyl-cyclopropyl}-vinyl)-4,5-bis-(tert-butyl-dimethyl-silanyloxy)-tetrahydro-pyran-2-yl]-acetic acid methyl ester