benzyl 4-ethyl-5-hydroxymethyl-3-methylpyrrole-2-carboxylate

Base Information

• Chemical Name: benzyl 4-ethyl-5-hydroxymethyl-3-methylpyrrole-2-carboxylate
• CAS No.: 13228-25-6
• Molecular Formula: C₁₆H₁₉NO₃
• Molecular Weight: 273.332
• Mol file: 13228-25-6.mol

Synonyms:benzyl 4-ethyl-5-hydroxymethyl-3-methylpyrrole-2-carboxylate

Chemical Property of benzyl 4-ethyl-5-hydroxymethyl-3-methylpyrrole-2-carboxylate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of benzyl 4-ethyl-5-hydroxymethyl-3-methylpyrrole-2-carboxylate

There total 3 articles about benzyl 4-ethyl-5-hydroxymethyl-3-methylpyrrole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

benzyl 5-(acetoxymethyl)-4-ethyl-3-methyl-1H-pyrrole-2-carboxylate (3750-36-5) → benzyl 4-ethyl-5-hydroxymethyl-3-methylpyrrole-2-carboxylate (13228-25-6)

Guidance literature:

With water; In acetone; for 8h;

Reference yield:

benzyl 4-ethyl-3,5-dimethylpyrrole-2-carboxylate (1925-61-7) → benzyl 4-ethyl-5-hydroxymethyl-3-methylpyrrole-2-carboxylate (13228-25-6)

Guidance literature:

With hydrogenchloride; iodosylbenzene; iron(III) meso-tetrakis-(2,6-dichloro-3-sulfonatophenyl)-β-octachloroporphyrin chloride; In acetonitrile; at 0 ℃; for 0.166667h;

DOI:10.1039/c39950002105

Reference yield:

→ benzyl 4-ethyl-5-hydroxymethyl-3-methylpyrrole-2-carboxylate (13228-25-6)

Guidance literature:

5-Dimethylaminocarbonyl-4-ethyl-3-methyl-pyrrol-2-carbonsaeure-benzylester (in THF), Diboran; nb. 5-Dimethylaminomethyl-4-ethyl-3-methyl-pyrrol-2-carbonsaeure-benzylester-Komplex m. Boran;

upstream raw materials:

benzyl 5-(acetoxymethyl)-4-ethyl-3-methyl-1H-pyrrole-2-carboxylate

benzyl 4-ethyl-3,5-dimethylpyrrole-2-carboxylate