5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin

Base Information

• Chemical Name: 5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin
• CAS No.: 71221-25-5
• Molecular Formula: C₄₆H₃₀F₂N₂O₂S₂
• Molecular Weight: 744.885
• Mol file: 71221-25-5.mol

Synonyms:5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin

Chemical Property of 5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin

There total 3 articles about 5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

2,5-bis[1-(4-methoxyphenyl)-1-hydroxymethyl]thiophene (71221-16-4,120450-72-8) + 2,5-bis[1-(4-fluorophenyl)-1-pyrrolomethyl]thiophene (398514-77-7) → 5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin (71221-25-5)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; for 1h; Heating;

DOI:10.1021/jm0103662

Reference yield:

2,5-bis[(4-fluorophenyl)-hydroxymethyl]-thiophene (71221-18-6) → 5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin (71221-25-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / BF₃*Et₂O / 1 h

2: 29 percent / TCBQ; BF₃*Et₂O / CH₂Cl₂ / 1 h / Heating

With boron trifluoride diethyl etherate; In dichloromethane;

DOI:10.1021/jm0103662

Reference yield:

pyrrole (109-97-7,30604-81-0) + 2,5-bis[(4-fluorophenyl)-hydroxymethyl]-thiophene (71221-18-6) + 2,5-bis[1-(4-methoxyphenyl)-1-hydroxymethyl]thiophene (71221-16-4,120450-72-8) → 5,10-bis-4-fluorophenyl-15,20-bis-4-methoxyphenyl-21,23-dithiaporphyrin (71221-25-5)

Guidance literature:

Multistep reaction; (i) ClCH₂CO₂H, (ii) /BRN= 1398586/, EtCO₂H, Ac₂O;

upstream raw materials:

pyrrole

2,5-bis[(4-fluorophenyl)-hydroxymethyl]-thiophene

2,5-bis[1-(4-methoxyphenyl)-1-hydroxymethyl]thiophene

2,5-bis[1-(4-fluorophenyl)-1-pyrrolomethyl]thiophene