Technology Process of C18H16BrNO3S
There total 7 articles about C18H16BrNO3S which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen bromide; acetic acid;
In
tetrahydrofuran;
at 0 ℃;
for 0.25h;
DOI:10.1002/ejoc.201100242
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: acetic acid; zinc / water / 1.83 h / 80 - 85 °C
2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 0 °C
2.2: 0 - 20 °C
3.1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine / 1,4-dioxane / 21 h / 100 °C
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran; water / 0.33 h / 0 °C
5.1: hydrogen bromide; acetic acid / tetrahydrofuran / 0.25 h / 0 °C
With
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride; hydrogen bromide; sodium hydride; acetic acid; triethylamine; zinc;
In
tetrahydrofuran; 1,4-dioxane; water; mineral oil;
3.1: Sonogashira coupling;
DOI:10.1002/ejoc.201100242
- Guidance literature:
-
Multi-step reaction with 3 steps
1: copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine / 1,4-dioxane / 21 h / 100 °C
2: tetrabutyl ammonium fluoride / tetrahydrofuran; water / 0.33 h / 0 °C
3: hydrogen bromide; acetic acid / tetrahydrofuran / 0.25 h / 0 °C
With
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); tetrabutyl ammonium fluoride; hydrogen bromide; acetic acid; triethylamine;
In
tetrahydrofuran; 1,4-dioxane; water;
1: Sonogashira coupling;
DOI:10.1002/ejoc.201100242
