diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

Base Information

Chemical Name:diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester
CAS No.:519753-22-1
Molecular Formula:C₃₅H₃₉BrN₂O₈
Molecular Weight:695.607
Hs Code.:

diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-<i>a</i>]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

Synonyms:diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

Suppliers and Price of diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

There total 5 articles about diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 519753-14-1
diethyl-carbamic acid 2-[1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

: 519753-22-1
diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

Guidance literature:: With N-Bromosuccinimide; In dichloromethane; at 20 ℃;
DOI:10.1016/S0040-4039(02)02887-3

Reference yield:

: 20628-06-2
2-hydroxy-4,5-dimethoxyacetophenone

: 519753-22-1
diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 79 percent / DMAP; Et₃N / CH₂Cl₂ / 20 °C

2: 70 percent / BnMe₃NBr₃ / CH₂Cl₂ / 0 - 20 °C

3: 81 percent / NaHCO₃ / acetonitrile / Heating

4: 99 percent / NBS / CH₂Cl₂ / 20 °C

With dmap; N-Bromosuccinimide; sodium hydrogencarbonate; triethylamine; benzyltrimethylazanium tribroman-2-uide; In dichloromethane; acetonitrile;
DOI:10.1016/S0040-4039(02)02887-3

Reference yield:

: 2033-89-8
3,4-dimethoxyphenol

: 519753-22-1
diethyl-carbamic acid 2-[3-bromo-1-(3,4-dimethoxy-phenyl)-8,9-dimethoxy-5,6-dihydro-pyrrolo[2,1-a]isoquinolin-2-yl]-4,5-dimethoxy-phenyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent / BF₃*Et₂O / 80 - 90 °C

2: 79 percent / DMAP; Et₃N / CH₂Cl₂ / 20 °C

3: 70 percent / BnMe₃NBr₃ / CH₂Cl₂ / 0 - 20 °C

4: 81 percent / NaHCO₃ / acetonitrile / Heating

5: 99 percent / NBS / CH₂Cl₂ / 20 °C

With dmap; N-Bromosuccinimide; boron trifluoride diethyl etherate; sodium hydrogencarbonate; triethylamine; benzyltrimethylazanium tribroman-2-uide; In dichloromethane; acetonitrile;
DOI:10.1016/S0040-4039(02)02887-3