C₁₆H₁₁Br₂NO

Base Information

• Chemical Name: C₁₆H₁₁Br₂NO
• CAS No.: 457948-81-1
• Molecular Formula: C₁₆H₁₁Br₂NO
• Molecular Weight: 393.077
• Mol file: 457948-81-1.mol

Synonyms:C₁₆H₁₁Br₂NO

Chemical Property of C₁₆H₁₁Br₂NO

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₁₆H₁₁Br₂NO

There total 5 articles about C₁₆H₁₁Br₂NO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.2%

→ C16H11Br2NO (457948-81-1)

Guidance literature:

Reference yield: 28.0%

C16H13NO (457948-80-0) → C16H11Br2NO (457948-81-1)

Guidance literature:

With N-Bromosuccinimide; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1039/c6md00381h

Reference yield:

meta-hydroxybenzaldehyde (100-83-4) → C16H11Br2NO (457948-81-1)

Guidance literature:

Multi-step reaction with 4 steps

1: tetra(n-butyl)ammonium hydrogensulfate; isopropyl nitrate; sulfuric acid / dichloromethane / 0.25 h / 20 °C / Inert atmosphere

2: iron; hydrogenchloride / ethanol; water / 5 h / Reflux

3: potassium hydroxide / ethanol / 0.67 h / 130 °C / Microwave irradiation; Inert atmosphere

4: N-Bromosuccinimide / dichloromethane / 2 h / 20 °C / Inert atmosphere

With hydrogenchloride; N-Bromosuccinimide; isopropyl nitrate; sulfuric acid; tetra(n-butyl)ammonium hydrogensulfate; iron; potassium hydroxide; In ethanol; dichloromethane; water; 3: |Friedlaender Quinoline Synthesis;

DOI:10.1039/c6md00381h

upstream raw materials:

3-phenyl-propionaldehyde

2-amino-3-hydroxybenzaldehyde

meta-hydroxybenzaldehyde

3-hydroxy-2-nitrobenzaldehyde

Downstream raw materials:

C₁₇H₁₂BrNO₂