(S)-2-amino-4-[2-chloro-4-(2-hydroxy-5-trifluoromethylphenylthio)phenyl]-2-propylbutylphosphoric acid monoester

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Chemical Name:(S)-2-amino-4-[2-chloro-4-(2-hydroxy-5-trifluoromethylphenylthio)phenyl]-2-propylbutylphosphoric acid monoester
CAS No.:1260511-46-3
Molecular Formula:C₂₀H₂₄ClF₃NO₅PS
Molecular Weight:513.902
Hs Code.:

Synonyms:(S)-2-amino-4-[2-chloro-4-(2-hydroxy-5-trifluoromethylphenylthio)phenyl]-2-propylbutylphosphoric acid monoester

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Chemical Property of (S)-2-amino-4-[2-chloro-4-(2-hydroxy-5-trifluoromethylphenylthio)phenyl]-2-propylbutylphosphoric acid monoester

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Technology Process of (S)-2-amino-4-[2-chloro-4-(2-hydroxy-5-trifluoromethylphenylthio)phenyl]-2-propylbutylphosphoric acid monoester

There total 2 articles about (S)-2-amino-4-[2-chloro-4-(2-hydroxy-5-trifluoromethylphenylthio)phenyl]-2-propylbutylphosphoric acid monoester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 1260512-04-6
(S)-2-t-butoxycarbonylamino-4-[4-(2-t-butoxycarbonyloxy-5-trifluoromethylphenylthio)-2-chlorophenyl]-1-dimethoxyphosphoryloxy-2-propylbutane

: 1260511-46-3
(S)-2-amino-4-[2-chloro-4-(2-hydroxy-5-trifluoromethylphenylthio)phenyl]-2-propylbutylphosphoric acid monoester

Guidance literature:: (S)-2-t-butoxycarbonylamino-4-[4-(2-t-butoxycarbonyloxy-5-trifluoromethylphenylthio)-2-chlorophenyl]-1-dimethoxyphosphoryloxy-2-propylbutane; With trimethylsilyl iodide; In acetonitrile; at 0 ℃; Inert atmosphere;

With water; In acetonitrile; at 0 ℃; for 1h;
DOI:10.1124/mol.115.100222