5-(4,4'-dimethoxytrityl)-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose

Base Information

• Chemical Name: 5-(4,4'-dimethoxytrityl)-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose
• CAS No.: 1220043-18-4
• Molecular Formula: C₃₆H₃₅NO₈
• Molecular Weight: 609.676
• Mol file: 1220043-18-4.mol

Synonyms:5-(4,4'-dimethoxytrityl)-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose

Chemical Property of 5-(4,4'-dimethoxytrityl)-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(4,4'-dimethoxytrityl)-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose

There total 1 articles about 5-(4,4'-dimethoxytrityl)-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

5-(4,4'-dimethoxytrityl)-3-O-tert-butyldimethylsilyloxy-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose (1220043-17-3) → 5-(4,4'-dimethoxytrityl)-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose (1220043-18-4)

Guidance literature:

With triethylamine tris(hydrogen fluoride); In tetrahydrofuran; at 20 ℃; for 48h;

DOI:10.1021/bc900529g

Reference yield: 86.0%

5-(4,4'-dimethoxytrityl)-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose (1220043-18-4) + 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine (124482-92-4,89992-70-1) → C45H52N3O9P (1220043-19-5)

Guidance literature:

With 1H-tetrazole; In acetonitrile; for 1.33333h;

DOI:10.1021/bc900529g

upstream raw materials:

5-(4,4'-dimethoxytrityl)-3-O-tert-butyldimethylsilyloxy-1,2-dideoxy-1-C-(2-phthalimidoxyethyl)-α-D-erythro-pentofuranose

Downstream raw materials:

C₄₅H₅₂N₃O₉P