5-(bromoacetamido)1-[2-(diethylamino)ethyl]-2-(4-ethoxybenzyl)benzimidazole

Base Information

Chemical Name:5-(bromoacetamido)1-[2-(diethylamino)ethyl]-2-(4-ethoxybenzyl)benzimidazole
CAS No.:91742-80-2
Molecular Formula:C₂₄H₃₁BrN₄O₂
Molecular Weight:487.44
Hs Code.:

Synonyms:5-(bromoacetamido)1-[2-(diethylamino)ethyl]-2-(4-ethoxybenzyl)benzimidazole

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Chemical Property of 5-(bromoacetamido)1-[2-(diethylamino)ethyl]-2-(4-ethoxybenzyl)benzimidazole

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Technology Process of 5-(bromoacetamido)1-[2-(diethylamino)ethyl]-2-(4-ethoxybenzyl)benzimidazole

There total 2 articles about 5-(bromoacetamido)1-[2-(diethylamino)ethyl]-2-(4-ethoxybenzyl)benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 13094-51-4
bromoacetic anhydride

: 5-amino-1-<2-(diethylamino)ethyl>-2-(4-ethoxybenzyl)benzimidazole methanesulfonate

: 91742-80-2
5-(bromoacetamido)1-[2-(diethylamino)ethyl]-2-(4-ethoxybenzyl)benzimidazole

Guidance literature:: With sodium hydrogencarbonate; In chloroform; for 0.75h;
DOI:10.1021/jm00378a008

Reference yield:

: 58-75-3
etonitazene methanesulfonate

: 91742-80-2
5-(bromoacetamido)1-[2-(diethylamino)ethyl]-2-(4-ethoxybenzyl)benzimidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / H₂ / 10percent Pd/C / H₂O; ethanol / 2 h / 2327.2 Torr

2: 80 percent / aq. NaHCO₃ / CHCl₃ / 0.75 h

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In ethanol; chloroform; water;
DOI:10.1021/jm00378a008