5'-O-(monomethoxytrityl)-N⁶2'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

Base Information

• Chemical Name: 5'-O-(monomethoxytrityl)-N⁶2'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine
• CAS No.: 148144-77-8
• Molecular Formula: C₅₇H₅₀N₈O₁₇
• Molecular Weight: 1119.07

Synonyms:5'-O-(monomethoxytrityl)-N⁶2'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

Chemical Property of 5'-O-(monomethoxytrityl)-N⁶2'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O-(monomethoxytrityl)-N⁶2'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

There total 5 articles about 5'-O-(monomethoxytrityl)-N⁶2'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-methyl-3-[2-(4-nitrophenyl)ethoxycarbonyl]imidazolium chloride (88091-70-7) + 5'-O-(monomethoxytrityl)-N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine (112141-39-6) → 5'-O-(monomethoxytrityl)-N62'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine (148144-77-8)

Guidance literature:

With dmap; In dichloromethane; for 2h; Ambient temperature;

DOI:10.1002/hlca.19930760122

Reference yield:

1-methyl-3-[2-(4-nitrophenyl)ethoxycarbonyl]imidazolium chloride (88091-70-7) → 5'-O-(monomethoxytrityl)-N62'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine (148144-77-8)

Guidance literature:

Multi-step reaction with 3 steps

2: 90 percent / pyridine / 18 h / Ambient temperature

3: 83 percent / 4-dimethylaminopyridine / CH₂Cl₂ / 2 h / Ambient temperature

With pyridine; dmap; In dichloromethane;

DOI:10.1002/hlca.19930760122

Reference yield:

N6-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine (88121-73-7) → 5'-O-(monomethoxytrityl)-N62'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine (148144-77-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / pyridine / 18 h / Ambient temperature

2: 83 percent / 4-dimethylaminopyridine / CH₂Cl₂ / 2 h / Ambient temperature

With pyridine; dmap; In dichloromethane;

DOI:10.1002/hlca.19930760122

upstream raw materials:

1-methyl-3-[2-(4-nitrophenyl)ethoxycarbonyl]imidazolium chloride

5'-O-(monomethoxytrityl)-N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

N⁶-<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

mono-4-methoxytrityl chloride

Downstream raw materials:

5'-O-(p-methoxyphenyldiphenylmethyl)adenosine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 148144-77-8 5'-O-(monomethoxytrityl)-N⁶2'-O,3'-O-tris<2-(4-nitrophenyl)ethoxycarbonyl>adenosine

Send

Send

Metric Ton KG G Pound L ML

Send

Send