4-(2-fluorophenyl)-5-[(4,5-diphenylimidazol-2-yl)thiomethyl]-2H-1,2,4-triazole-3-thione

Base Information

Chemical Name:4-(2-fluorophenyl)-5-[(4,5-diphenylimidazol-2-yl)thiomethyl]-2H-1,2,4-triazole-3-thione
CAS No.:1391014-09-7
Molecular Formula:C₂₄H₁₈FN₅S₂
Molecular Weight:459.571
Hs Code.:

Synonyms:4-(2-fluorophenyl)-5-[(4,5-diphenylimidazol-2-yl)thiomethyl]-2H-1,2,4-triazole-3-thione

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Chemical Property of 4-(2-fluorophenyl)-5-[(4,5-diphenylimidazol-2-yl)thiomethyl]-2H-1,2,4-triazole-3-thione

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Technology Process of 4-(2-fluorophenyl)-5-[(4,5-diphenylimidazol-2-yl)thiomethyl]-2H-1,2,4-triazole-3-thione

There total 2 articles about 4-(2-fluorophenyl)-5-[(4,5-diphenylimidazol-2-yl)thiomethyl]-2H-1,2,4-triazole-3-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1391014-04-2
C₂₄H₂₀FN₅OS₂

: 1391014-09-7
4-(2-fluorophenyl)-5-[(4,5-diphenylimidazol-2-yl)thiomethyl]-2H-1,2,4-triazole-3-thione

Guidance literature:: C₂₄H₂₀FN₅OS₂; With sodium hydroxide; In water; for 8h; Reflux;

With hydrogenchloride; In water; at 20 ℃;
DOI:10.3987/COM-12-12456

Reference yield:

: 38985-64-7
o-fluorophenyl isothiocyanate

: 1391014-09-7
4-(2-fluorophenyl)-5-[(4,5-diphenylimidazol-2-yl)thiomethyl]-2H-1,2,4-triazole-3-thione

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethanol / 6 h / Reflux

2.1: sodium hydroxide / water / 8 h / Reflux

2.2: 20 °C

With sodium hydroxide; In ethanol; water;
DOI:10.3987/COM-12-12456