(N-B)-chloro[5-chloro-2-(dimethylaminomethyl)phenyl]phenylborane

Base Information

• Chemical Name: (N-B)-chloro[5-chloro-2-(dimethylaminomethyl)phenyl]phenylborane
• CAS No.: 903525-86-0
• Molecular Formula: C₁₅H₁₆BCl₂N
• Molecular Weight: 292.016
• Mol file: 903525-86-0.mol

Synonyms:(N-B)-chloro[5-chloro-2-(dimethylaminomethyl)phenyl]phenylborane

Chemical Property of (N-B)-chloro[5-chloro-2-(dimethylaminomethyl)phenyl]phenylborane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (N-B)-chloro[5-chloro-2-(dimethylaminomethyl)phenyl]phenylborane

There total 1 articles about (N-B)-chloro[5-chloro-2-(dimethylaminomethyl)phenyl]phenylborane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 22.0%

N,N-dimethyl-4-chlorobenzylamine (15184-98-2) + phenylborondichloride (873-51-8) → (N-B)-chloro[5-chloro-2-(dimethylaminomethyl)phenyl]phenylborane (903525-86-0)

Guidance literature:

N,N-dimethyl-4-chlorobenzylamine; With n-butyllithium; In hexane;

phenylborondichloride; In hexane; at 20 ℃; for 3h;

DOI:10.1246/bcsj.79.796

Reference yield: 88.0%

(N-B)-chloro[5-chloro-2-(dimethylaminomethyl)phenyl]phenylborane (903525-86-0) + silver(I) pentafluoropropionate (509-09-1) → (+/-)-(N-B)-[5-chloro-2-(dimethylaminomethyl)phenyl](pentafluoropropionyloxy)phenylborane

Guidance literature:

In dichloromethane; at 20 ℃; for 3h;

DOI:10.1246/bcsj.79.796

Reference yield:

(N-B)-chloro[5-chloro-2-(dimethylaminomethyl)phenyl]phenylborane (903525-86-0) → (S)-(+)-(N-B)-[5-chloro-2-(dimethylaminomethyl)phenyl](pentafluoropropionyloxy)phenylborane

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / CH₂Cl₂ / 3 h / 20 °C

2: Daicel Chiralpak AD / hexane; propan-2-ol

With Daicel Chiralpak AD; In hexane; dichloromethane; isopropyl alcohol;

DOI:10.1246/bcsj.79.796

upstream raw materials:

N,N-dimethyl-4-chlorobenzylamine

phenylborondichloride