methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate

Base Information

Chemical Name:methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate
CAS No.:107474-66-8
Molecular Formula:C₁₇H₂₀N₂O₄
Molecular Weight:316.357
Hs Code.:

Synonyms:methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate

Suppliers and Price of methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Matrix Scientific
6-tert-Butyl2-methyl7,8-dihydropyrrolo-[3,2-e]indole-2,6(3H)-dicarboxylate 97%
10g
$ 3780.00

Matrix Scientific
6-tert-Butyl2-methyl7,8-dihydropyrrolo-[3,2-e]indole-2,6(3H)-dicarboxylate 97%
5g
$ 3060.00

Total 3 raw suppliers

Chemical Property of methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate

Chemical Property:

Boiling Point:473.9±33.0 °C(Predicted)
Density:1.280±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

6-tert-Butyl2-methyl7,8-dihydropyrrolo-[3,2-e]indole-2,6(3H)-dicarboxylate 97% ^*data from reagent suppliers

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Technology Process of methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate

There total 5 articles about methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 107474-63-5
methyl 1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate

: 107474-66-8
methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate

Guidance literature:: In tetrahydrofuran; at 25 ℃; for 16h;

Reference yield:

: 1074-86-8
4-formyl indole

: 107474-66-8
methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1: 96 percent / sodium methoxide / methanol / 3 h / 0 °C

2: 71 percent / various solvent(s) / 4 h / Heating

3: 79 percent / NaCNBH₃ / acetic acid / 2 h / 15 - 17 °C

4: 82 percent / tetrahydrofuran / 13.5 h / 23 °C

With sodium methylate; sodium cyanoborohydride; In tetrahydrofuran; methanol; acetic acid;
DOI:10.1021/jo00384a026

Reference yield:

: 107474-65-7
methyl pyrrolo<3,2-e>indole-2-carboxylate

: 107474-66-8
methyl 3-(tert-butyloxycarbonyl)-1,2-dihydro-3H-pyrrolo<3,2-e>indole-7-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / NaCNBH₃ / acetic acid / 2 h / 15 - 17 °C

2: 82 percent / tetrahydrofuran / 13.5 h / 23 °C

With sodium cyanoborohydride; In tetrahydrofuran; acetic acid;
DOI:10.1021/jo00384a026