C₃₃H₅₁BrO₈Si

Base Information

Chemical Name:C₃₃H₅₁BrO₈Si
CAS No.:814919-96-5
Molecular Formula:C₃₃H₅₁BrO₈Si
Molecular Weight:683.753
Hs Code.:

C<sub>33</sub>H<sub>51</sub>BrO<sub>8</sub>Si

Synonyms:C₃₃H₅₁BrO₈Si

Suppliers and Price of C₃₃H₅₁BrO₈Si

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C₃₃H₅₁BrO₈Si

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C₃₃H₅₁BrO₈Si

There total 23 articles about C₃₃H₅₁BrO₈Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 814920-09-7
C₂₉H₄₄O₇Si

: 2032-35-1
Bromoacetaldehyde diethyl acetal

: 814919-96-5
C₃₃H₅₁BrO₈Si

Guidance literature:: With zinc(II) chloride; In dichloromethane; for 0.75h;
DOI:10.1021/jo048681u

Reference yield:

: 312923-90-3
(1S,3R,7R,8S,9R,10S,11S)-9-Benzyloxymethyl-10-hydroxymethyl-11-methyl-7-trimethylsilanyloxy-4-oxa-tricyclo[5.3.1.0^3,8]undecan-5-one

: 814919-96-5
C₃₃H₅₁BrO₈Si

Guidance literature:: Multi-step reaction with 21 steps

1.1: 29 percent / diacetoxyiodobenzene; iodine / CH₂Cl₂ / 0.83 h / 0 °C / Irradiation

2.1: 86 percent / i-Pr₂NEt / CH₂Cl₂ / 10 h / 20 °C

3.1: O₃ / CH₂Cl₂ / 0.25 h / -78 °C

3.2: 83 percent / PPh₃ / CH₂Cl₂ / -78 - 20 °C

4.1: Zn(BH₄)2 / diethyl ether / 0.5 h / 0 °C

5.1: tetrabutylammonium fluoride / tetrahydrofuran / 0.17 h / 0 °C

6.1: 2.25 g / PPTS / acetone / 14 h / 20 °C

7.1: LiHMDS; HMPA / tetrahydrofuran / 1.5 h / -78 °C

7.2: 86 percent / tetrahydrofuran / 0.92 h / -78 - -40 °C

8.1: O₃ / CH₂Cl₂ / 0.08 h / -78 °C

8.2: triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

9.1: 197 mg / NaBH₄ / CH₂Cl₂; methanol / 0.08 h / 20 °C

10.1: 97 percent / n-Bu₃P / tetrahydrofuran / 1.67 h / -78 - 20 °C

11.1: 252 mg / H₂O₂ / tetrahydrofuran / 12 h / 20 °C

12.1: 335 mg / LiAlH₄ / dioxane / 0.02 h / Heating

13.1: 345 mg / Et₃N; DMAP / CH₂Cl₂ / 1.17 h / 20 °C

14.1: 93 percent / 4-methylmorpholine N-oxide / TPAP / acetonitrile / 1 h / 20 °C

15.1: O₃ / CH₂Cl₂ / 0.67 h / -78 °C

15.2: 88 percent / triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

16.1: 86 percent / SmI₂; HMPA / tetrahydrofuran / 0.75 h / -40 - 0 °C

17.1: 87 percent / DMAP / tetrahydrofuran / 6 h / 20 °C

18.1: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.67 h / 20 °C

19.1: 98 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.58 h / 20 °C

20.1: 90 percent / NaBH₄; CeCl₃*7H₂O / methanol / 0.25 h / 0 °C

21.1: 77 percent / zinc chloride / CH₂Cl₂ / 0.75 h

With N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; sodium tetrahydroborate; lithium aluminium tetrahydride; samarium diiodide; cerium(III) chloride; zinc(II) tetrahydroborate; tributylphosphine; [bis(acetoxy)iodo]benzene; tetrabutyl ammonium fluoride; dihydrogen peroxide; iodine; pyridinium p-toluenesulfonate; Dess-Martin periodane; ozone; 4-methylmorpholine N-oxide; triethylamine; N-ethyl-N,N-diisopropylamine; zinc(II) chloride; lithium hexamethyldisilazane; tetrapropylammonium perruthennate; In tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; dichloromethane; acetone; acetonitrile; 11.1: Grieco olefination / 19.1: Dess-Martin oxidation;
DOI:10.1021/jo048681u

Reference yield:

: (1S,3R,7S,8S,9R,10R,11R)-9-Benzyloxymethyl-7,11-dihydroxy-10-(2-trimethylsilanyl-ethoxymethoxymethyl)-4-oxa-tricyclo[5.3.1.0^3,8]undecan-5-one

: 814919-96-5
C₃₃H₅₁BrO₈Si

Guidance literature:: Multi-step reaction with 16 steps

1.1: 2.25 g / PPTS / acetone / 14 h / 20 °C

2.1: LiHMDS; HMPA / tetrahydrofuran / 1.5 h / -78 °C

2.2: 86 percent / tetrahydrofuran / 0.92 h / -78 - -40 °C

3.1: O₃ / CH₂Cl₂ / 0.08 h / -78 °C

3.2: triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

4.1: 197 mg / NaBH₄ / CH₂Cl₂; methanol / 0.08 h / 20 °C

5.1: 97 percent / n-Bu₃P / tetrahydrofuran / 1.67 h / -78 - 20 °C

6.1: 252 mg / H₂O₂ / tetrahydrofuran / 12 h / 20 °C

7.1: 335 mg / LiAlH₄ / dioxane / 0.02 h / Heating

8.1: 345 mg / Et₃N; DMAP / CH₂Cl₂ / 1.17 h / 20 °C

9.1: 93 percent / 4-methylmorpholine N-oxide / TPAP / acetonitrile / 1 h / 20 °C

10.1: O₃ / CH₂Cl₂ / 0.67 h / -78 °C

10.2: 88 percent / triphenylphosphine / CH₂Cl₂ / -78 - 20 °C

11.1: 86 percent / SmI₂; HMPA / tetrahydrofuran / 0.75 h / -40 - 0 °C

12.1: 87 percent / DMAP / tetrahydrofuran / 6 h / 20 °C

13.1: 96 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.67 h / 20 °C

14.1: 98 percent / Dess-Martin periodinane / CH₂Cl₂ / 0.58 h / 20 °C

15.1: 90 percent / NaBH₄; CeCl₃*7H₂O / methanol / 0.25 h / 0 °C

16.1: 77 percent / zinc chloride / CH₂Cl₂ / 0.75 h

With N,N,N,N,N,N-hexamethylphosphoric triamide; dmap; sodium tetrahydroborate; lithium aluminium tetrahydride; samarium diiodide; cerium(III) chloride; tributylphosphine; tetrabutyl ammonium fluoride; dihydrogen peroxide; pyridinium p-toluenesulfonate; Dess-Martin periodane; ozone; 4-methylmorpholine N-oxide; triethylamine; zinc(II) chloride; lithium hexamethyldisilazane; tetrapropylammonium perruthennate; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; acetone; acetonitrile; 6.1: Grieco olefination / 14.1: Dess-Martin oxidation;
DOI:10.1021/jo048681u